微量即时检测分析方法。
Small-volume point-of-care analytical methods.
机构信息
Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, 300, Taiwan.
出版信息
Sci Rep. 2020 Aug 27;10(1):14230. doi: 10.1038/s41598-020-70903-4.
Abstract
Detecting clinically relevant diagnostic biomarkers, suitable for point-of-care detection, may facilitate rapid treatment and prevention of disease. However, medical diagnosis for which there are limited quantities of testable tissue or fluid, require point-of-care technologies with superior sensitivity and specificity. The purpose of this Editorial is to provide an overview of the Collection’s content, comprising original research into fluidics-based diagnostic platforms—specifically those made of paper or other low-cost materials, that can suitably operate with tiny sample volumes from mL to nL. In particular, we will focus on the clinical applications of such research, with potential uses in a number of fields including combating the COVID-19 pandemic for instance.
摘要
检测具有临床意义的诊断生物标志物，适合即时检测，可能有助于快速治疗和预防疾病。然而，对于那些可检测的组织或液体数量有限的医学诊断，则需要具有更高灵敏度和特异性的即时检测技术。本社论的目的是概述该专集的内容，其中包括基于流体的诊断平台的原始研究，特别是那些由纸张或其他低成本材料制成的平台，这些平台可以适当地处理从 mL 到 nL 的小体积样本。特别地，我们将重点关注此类研究的临床应用，例如在抗击 COVID-19 大流行等多个领域具有潜在用途。
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