Department of Rheumatology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, colonia Sección XVI, 14080, Ciudad de México, Mexico.
Curr Rheumatol Rep. 2020 Aug 27;22(10):72. doi: 10.1007/s11926-020-00952-1.
Vasculitis can cause heart disease and are associated with premature atherosclerosis, causing increased morbidity and mortality. Consequently, it is important to know how they can affect the cardiovascular system in order to detect and treat the abnormalities in earlier phases.
A clear increasing trend of inpatient burden of myocardial infarction and thromboembolic events in granulomatosis with polyangiitis has been observed lately. Behçet's disease has been linked to an increased risk of atrial fibrillation. Studies showing increased atherosclerosis and thromboembolic phenomena in vasculitis are continuously published. Improvement in imaging techniques has consistently showed that subclinical cardiovascular involvement is frequent. Vasculitis may affect seriously the cardiovascular system causing an important increase in morbidity and mortality. Subclinical involvement is frequent. Early treatment with immunosuppression and sometimes surgery, is of paramount importance to improve the prognosis.
血管炎可导致心脏疾病,并与早发动脉粥样硬化相关,从而增加发病率和死亡率。因此,了解血管炎如何影响心血管系统以在早期阶段发现和治疗异常非常重要。
最近观察到,巨细胞动脉炎的住院心肌梗死和血栓栓塞事件负担呈明显上升趋势。白塞病与心房颤动风险增加相关。不断有研究表明血管炎存在动脉粥样硬化和血栓栓塞现象增加。影像学技术的改进一直表明,亚临床心血管受累较为常见。血管炎可严重影响心血管系统,导致发病率和死亡率显著增加。亚临床受累较为常见。早期免疫抑制治疗,有时还需要手术治疗,对改善预后至关重要。