氟代脱氧葡萄糖正电子发射断层显像/磁共振成像（FDG-PET/MR）能否有助于克服序贯性磁共振成像（MRI）和氟代脱氧葡萄糖正电子发射断层显像（PET-FDG）在鉴别高级别胶质瘤复发/进展与放射性坏死方面的局限性？
Can FDG-PET/MR help to overcome limitations of sequential MRI and PET-FDG for differential diagnosis between recurrence/progression and radionecrosis of high-grade gliomas?
作者信息
Pyatigorskaya N, Sgard B, Bertaux M, Yahia-Cherif L, Kas A
机构信息
Sorbonne Université, Assistance Publique Hôpitaux de Paris, Neuroradiology Department, Pitié-Salpêtrière -Charles Foix Hospital, Paris, France; Sorbonne Université, Univ Paris 6, UMR S 1127, CNRS UMR 722, Institut du Cerveau et de la Moelle épinière, F-75013 Paris, France.
Assistance Publique Hôpitaux de Paris, Nuclear Medicine Department, Pitié Salpêtrière-Charles Foix Hospital, AP-HP, 47-83 Boulevard de l'Hôpital, 75651 Paris CEDEX 13, France.
出版信息
J Neuroradiol. 2021 May;48(3):189-194. doi: 10.1016/j.neurad.2020.08.003. Epub 2020 Aug 25.
The aim of our study was assessing the potential of FDG-PET-MRI to overcome limitations of separately performed MRI and PET-FDG and improving the performance of high-grade gliomas evaluation. Combined PET-MRI analysis allowed differentiating between recurrence/progression and radionecrosis with improved diagnostic accuracy (95% vs 63% for PET and 82% for MRI). FDG being a reliable, cost-saving tracer in this indication, combined FDG PET-MRI analysis could play a significant role in the follow-up of high-grade brain tumors.
我们研究的目的是评估氟代脱氧葡萄糖正电子发射断层扫描-磁共振成像（FDG-PET-MRI）克服单独进行的MRI和PET-FDG的局限性以及提高高级别胶质瘤评估性能的潜力。PET-MRI联合分析能够区分复发/进展与放射性坏死，诊断准确性得到提高（PET为95%，MRI为82%，单独PET为63%）。鉴于FDG在该适应症中是一种可靠且节省成本的示踪剂，FDG PET-MRI联合分析在高级别脑肿瘤的随访中可发挥重要作用。
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