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小儿急性阑尾炎行阑尾切除术的结局:一项回顾性队列研究的结果。

Outcomes after appendectomy in children with acute appendicitis treated at a tertiary paediatric centre: results from a retrospective cohort study.

机构信息

Department of Paediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam & Vrije Universiteit Amsterdam, PO Box 22660, 1100DD, Amsterdam, The Netherlands.

出版信息

Langenbecks Arch Surg. 2021 Feb;406(1):163-169. doi: 10.1007/s00423-020-01976-y. Epub 2020 Aug 28.

Abstract

PURPOSE

In general, an appendectomy is presumed to have a limited burden of disease. However, in current literature, reported complication rates vary. This study aims to provide additional insights in the incidence of post-appendectomy complications in children with acute appendicitis.

METHODS

This retrospective cohort study included children (0-17 years old) that underwent appendectomy at our tertiary referral centre for suspected acute appendicitis (January 2011-December 2018). Children referred to our centre, and those that underwent non-operative treatment were excluded. Post-appendectomy complications were recorded from electronic medical charts using predefined definitions and classified as severe (Clavien-Dindo III-IV) or less severe (Clavien-Dindo I-II).

RESULTS

A total of 131 children were included. Simple and complex appendicitis was diagnosed in 66 (50%) and 60 (46%) children, respectively. A non-inflamed appendix was seen in five (4%) children. One or more complications were identified in 33 (25%) patients. Eight (12%) children with simple appendicitis developed a complication, three of these were severe. In children with complex appendicitis, 23 (38%) children developed a complication, 14 of these were severe.

CONCLUSION

This study shows a high rate of complications compared with current literature, both in children with simple and complex appendicitis. This is probably the result of our definition of complications and being a tertiary referral centre receiving more severe appendicitis cases. However, these results still show that appendectomy is not always a routine procedure with only few complications. Substantiating the need to keep optimizing treatment for children with appendicitis.

摘要

目的

一般来说,阑尾切除术被认为疾病负担有限。然而,在当前的文献中,报告的并发症发生率有所不同。本研究旨在为儿童急性阑尾炎阑尾切除术后并发症的发生率提供更多的见解。

方法

本回顾性队列研究纳入了在我们的三级转诊中心因疑似急性阑尾炎而行阑尾切除术的儿童(2011 年 1 月至 2018 年 12 月)。排除了转诊至我们中心的儿童和接受非手术治疗的儿童。通过电子病历记录阑尾切除术后并发症,使用预定义的定义对其进行分类,分为严重(Clavien-Dindo III-IV)或不严重(Clavien-Dindo I-II)。

结果

共纳入 131 名儿童。单纯性和复杂性阑尾炎分别在 66 名(50%)和 60 名(46%)儿童中诊断。5 名(4%)儿童的阑尾未见炎症。33 名(25%)患者出现 1 种或多种并发症。8 名(12%)单纯性阑尾炎患儿发生并发症,其中 3 例为严重并发症。复杂性阑尾炎患儿中,23 名(38%)发生并发症,其中 14 名严重并发症。

结论

与目前的文献相比,本研究显示单纯性和复杂性阑尾炎患儿的并发症发生率均较高。这可能是由于我们对并发症的定义以及作为一个接收更多严重阑尾炎病例的三级转诊中心所致。然而,这些结果仍表明阑尾切除术并不总是一种常规手术,只有少数并发症。这证明需要不断优化儿童阑尾炎的治疗方法。

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