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对比观察侧视十二指肠镜和前视胃镜在毕Ⅱ式胃切除术后患者行内镜逆行胰胆管造影术的效果。

A comparative study of side-viewing duodenoscope and forward-viewing gastroscope to perform endoscopic retrograde cholangiopancreatography in patients with Billroth II gastrectomy.

机构信息

Department of Gastroenterology, Türkiye Yüksek İhtisas Education and Research Hospital, Ankara, Turkey.

出版信息

Surg Endosc. 2021 Aug;35(8):4222-4230. doi: 10.1007/s00464-020-07904-x. Epub 2020 Aug 28.

Abstract

BACKGROUND/AIM: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Billroth II gastrectomy is a difficult procedure. Although different endoscopes are used in these patients, comparative studies are limited. The aim of this study was to assess the efficacy and the safety of the forward-viewing gastroscope compared with the side-viewing duodenoscope.

MATERIALS AND METHODS

This study was conducted on 75 Billroth II gastrectomy patients who underwent ERCP by the same experienced endoscopist. Procedures were performed using side-viewing duodenoscope in the first 41 patients and forward-viewing gastroscope in the subsequent 34 patients. The success and complication rates of ERCP were compared between the two groups.

RESULTS

Afferent loop intubation was achieved in 39 patients (95.1%) in the side-viewing duodenoscope group and in 34 patients (100%) in the forward-viewing gastroscope group (P = 0.49). The rates of reaching the papilla was 70.7% (n = 29) and 91.1% (n = 31), respectively (P = 0.06). Cannulation success rate after reaching the papilla was 100% in the side-viewing duodenoscope group and 90.3% in the forward-viewing gastroscope group. In the side-viewing duodenoscope group, 11 patients underwent sphincterotomy (EST), 14 patients underwent both EST and endoscopic papillary balloon dilatation (EPBD), and 4 patients underwent only EPBD. All but one patients in the forward-viewing gastroscope group underwent EPBD without EST. The technical and the clinical success rate did not statistically differ between the groups (70.7% vs. 82.3%, 68.3% vs. 79.4%, respectively). Adverse events included jejunal perforation in one patient (2.4%) in the side-viewing duodenoscope group, and pancreatitis in one patient (2.9%) in the forward-viewing gastroscope group (P > 0.05).

CONCLUSION

This study indicates that forward-viewing gastroscope is as effective as side-viewing duodenoscope for ERCP in patients with Billroth II gastrectomy. Furthermore, EPBD without prior EST appears to be a safe and effective procedure in these patients.

摘要

背景/目的:毕罗氏 II 式胃切除术后行内镜逆行胰胆管造影术(ERCP)较为困难。尽管在这些患者中使用了不同的内镜,但相关比较研究有限。本研究旨在评估前视式胃镜与侧视式十二指肠镜的疗效和安全性。

材料和方法

本研究纳入了 75 例由同一位经验丰富的内镜医生行 ERCP 的毕罗氏 II 式胃切除术后患者。前 41 例患者采用侧视式十二指肠镜进行操作,后 34 例患者采用前视式胃镜进行操作。比较两组患者 ERCP 的成功率和并发症发生率。

结果

在侧视式十二指肠镜组中,39 例(95.1%)患者成功插管进入输入袢,前视式胃镜组中 34 例(100%)患者成功插管进入输入袢(P=0.49)。到达乳头的比例分别为 70.7%(n=29)和 91.1%(n=31)(P=0.06)。到达乳头后行乳头切开术的成功率在侧视式十二指肠镜组为 100%,在前视式胃镜组为 90.3%。在侧视式十二指肠镜组中,11 例患者行括约肌切开术(EST),14 例患者行 EST 和内镜乳头气囊扩张术(EPBD),4 例患者仅行 EPBD。在前视式胃镜组中,所有患者均行 EPBD 治疗,无一例行 EST。两组的技术成功率和临床成功率无统计学差异(分别为 70.7% vs. 82.3%,68.3% vs. 79.4%)。不良事件包括侧视式十二指肠镜组 1 例(2.4%)患者发生空肠穿孔,前视式胃镜组 1 例(2.9%)患者发生胰腺炎(P>0.05)。

结论

本研究表明,前视式胃镜用于毕罗氏 II 式胃切除术后患者的 ERCP 与侧视式十二指肠镜同样有效。此外,对于这些患者,在未行 EST 的情况下行 EPBD 似乎是一种安全有效的治疗方法。

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