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毕罗Ⅱ式吻合术后内镜逆行胰胆管造影术的临床结果:胃镜与十二指肠镜的比较

Clinical outcomes of endoscopic retrograde cholangiopancreatography after Billroth II anastomosis: a comparison of gastroscope and duodenoscope.

作者信息

Lee Kang Ho, Yim Gwang Hyo, Han Jimin, Jeong Han Taek

机构信息

Department of Internal Medicine, Daegu Catholic University School of Medicine, 33 Duryugongwon-ro 17-gil, Nam-gu, Daegu, 42472, Korea.

出版信息

BMC Gastroenterol. 2025 May 15;25(1):373. doi: 10.1186/s12876-025-03973-1.

DOI:10.1186/s12876-025-03973-1
PMID:40375138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12079895/
Abstract

BACKGROUND

Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Billroth II anastomosis is challenging due to post-surgical anatomical alterations. This study aims to compare the clinical outcomes of using a duodenoscope and a cap-assisted gastroscope in these patients.

METHODS

Seventy-nine patients with Billroth II anastomosis and a naïve papilla were included in the study. ERCP was performed using either a cap-assisted gastroscope (n = 45) or a duodenoscope (n = 34). The primary outcome was the cannulation success rates, while secondary outcomes included clinical success rates, cannulation time, procedure duration, and complications.

RESULTS

Afferent limb intubation was successful in 67.1% of patients. Among these, selective biliary cannulation (SBC) was achieved in 73.6%, with no significant difference between the two groups. However, cannulation time was significantly longer in the cap-assisted gastroscope group (7.6 min vs. 5.8 min, p = 0.011). Complications occurred only in the cap-assisted gastroscope group, including one perforation (2.2%) and two cases of pancreatitis (4.4%), though the overall complication rate was not significantly different. Among the 40 patients (50.7%) who failed ERCP, percutaneous transhepatic biliary drainage (PTBD) was the most common rescue intervention (55%), followed by other procedures, including percutaneous gallbladder drainage, repeated ERCP, surgery, and conservative treatment.

CONCLUSIONS

Both cap-assisted gastroscopes and duodenoscopes are viable options for ERCP in patients with Billroth II anastomosis. However, cannulation time was significantly shorter in the duodenoscope group.

摘要

背景

由于手术导致的解剖结构改变,毕罗Ⅱ式吻合术后患者的内镜逆行胰胆管造影(ERCP)具有挑战性。本研究旨在比较在这些患者中使用十二指肠镜和帽辅助胃镜的临床结果。

方法

79例毕罗Ⅱ式吻合且乳头未处理过的患者纳入本研究。使用帽辅助胃镜(n = 45)或十二指肠镜(n = 34)进行ERCP。主要结局是插管成功率,次要结局包括临床成功率、插管时间、操作持续时间和并发症。

结果

67.1%的患者输入袢插管成功。其中,73.6%实现了选择性胆管插管(SBC),两组间无显著差异。然而,帽辅助胃镜组的插管时间显著更长(7.6分钟对5.8分钟,p = 0.011)。并发症仅发生在帽辅助胃镜组,包括1例穿孔(2.2%)和2例胰腺炎(4.4%),尽管总体并发症发生率无显著差异。在40例(50.7%)ERCP失败的患者中,经皮肝穿刺胆道引流(PTBD)是最常见的挽救性干预措施(55%),其次是其他操作,包括经皮胆囊引流、重复ERCP、手术和保守治疗。

结论

帽辅助胃镜和十二指肠镜都是毕罗Ⅱ式吻合术后患者进行ERCP的可行选择。然而,十二指肠镜组的插管时间显著更短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/b324ef976cc6/12876_2025_3973_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/07002d318631/12876_2025_3973_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/dd116b8984bd/12876_2025_3973_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/e4d7bdd59c30/12876_2025_3973_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/b324ef976cc6/12876_2025_3973_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/07002d318631/12876_2025_3973_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/dd116b8984bd/12876_2025_3973_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/e4d7bdd59c30/12876_2025_3973_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8011/12079895/b324ef976cc6/12876_2025_3973_Fig4_HTML.jpg

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本文引用的文献

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Med Sci (Basel). 2025 Feb 11;13(1):18. doi: 10.3390/medsci13010018.
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Synergistic effect of independent risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis: a multicenter retrospective study in Japan.内镜逆行胰胆管造影术后胰腺炎独立危险因素的协同效应:日本一项多中心回顾性研究
Clin Endosc. 2024 Jul;57(4):508-514. doi: 10.5946/ce.2023.203. Epub 2024 Apr 18.
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Single-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography in patients with surgically altered anatomy: a technical review.
单气囊小肠镜辅助内镜逆行胰胆管造影术在解剖结构改变的手术患者中的应用:技术综述
Clin Endosc. 2023 Nov;56(6):716-725. doi: 10.5946/ce.2023.023. Epub 2023 Apr 17.
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Prolonged cannulation time is an independent risk factor for moderate-to-severe post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis: a large cohort study.长时间置管时间是中度至重度内镜逆行胰胆管造影术(ERCP)后胰腺炎的独立危险因素:一项大型队列研究。
Ann Transl Med. 2023 Mar 15;11(5):188. doi: 10.21037/atm-22-4697. Epub 2023 Mar 6.
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A comparative study of side-viewing duodenoscope and forward-viewing gastroscope to perform endoscopic retrograde cholangiopancreatography in patients with Billroth II gastrectomy.对比观察侧视十二指肠镜和前视胃镜在毕Ⅱ式胃切除术后患者行内镜逆行胰胆管造影术的效果。
Surg Endosc. 2021 Aug;35(8):4222-4230. doi: 10.1007/s00464-020-07904-x. Epub 2020 Aug 28.
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ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.内镜逆行胰胆管造影(ERCP)相关不良事件:欧洲胃肠道内镜学会(ESGE)指南。
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