Department of Cardiology, Base Hospital Delhi Cantt, New Delhi, India.
Department of Cardiology, Base Hospital Delhi Cantt, New Delhi, India.
Indian Heart J. 2020 Jul-Aug;72(4):239-243. doi: 10.1016/j.ihj.2020.03.013. Epub 2020 Apr 13.
The aim of this study was to evaluate the feasibility of heparinised saline as flushing media for frequency-domain optical coherence tomography (FD-OCT) image acquisition during percutaneous coronary intervention (PCI) optimisation.
Twenty-seven patients undergoing FD-OCT-guided PCI were enrolled. Heparinised saline was injected into the coronary during FD-OCT image acquisition. A total of 118 runs were analysed for image quality and diagnostic value. FD-OCT runs were categorised as follows: good runs (GRs), clinically usable runs (CURs) and clinically not usable runs (NURs); GRs and CURs were combined as clinically effective runs (ERs). Saline FD-OCT enabled visualisation of all possible coronary lesions. Of the 118 runs analysed, 61%, 27.1%, 11.9% and 88.1% were GRs, CURs, NURs and ERs, respectively. Sixty-one percent of total runs were left coronary system (LCS) and 39% were right coronary system (RCS) runs. Among LCS runs, 55.6%, 30.6%, 13.8% and 86.2% were GRs, CURs, NURs and ERs, respectively. Among RCS runs, 69.6%, 21.7%, 8.7% and 91.3% were GRs, CURs, NURs and ERs, respectively.
This is the first study to demonstrate the technical feasibility of isolated saline FD-OCT for PCI optimisation.
本研究旨在评估肝素化盐水作为经皮冠状动脉介入治疗（PCI）优化过程中频域光相干断层扫描（FD-OCT）图像采集冲洗介质的可行性。
本研究纳入了 27 例行 FD-OCT 引导 PCI 的患者。在 FD-OCT 图像采集过程中向冠状动脉内注射肝素化盐水。共对 118 次运行进行了图像质量和诊断价值分析。FD-OCT 运行分为以下几类：良好运行（GRs）、临床可用运行（CURs）和临床不可用运行（NURs）；GRs 和 CURs 合并为临床有效运行（ERs）。盐水 FD-OCT 能够可视化所有可能的冠状动脉病变。在分析的 118 次运行中，GRs、CURs、NURs 和 ERs 分别占 61%、27.1%、11.9%和 88.1%。总运行中有 61%为左冠状动脉系统（LCS），39%为右冠状动脉系统（RCS）。在 LCS 运行中，GRs、CURs、NURs 和 ERs 分别占 55.6%、30.6%、13.8%和 86.2%。在 RCS 运行中，GRs、CURs、NURs 和 ERs 分别占 69.6%、21.7%、8.7%和 91.3%。
这是第一项证明肝素化盐水在 PCI 优化中具有技术可行性的研究。
