Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an, 710062, China.
Anal Sci. 2021 Feb 10;37(2):293-299. doi: 10.2116/analsci.20P229. Epub 2020 Aug 28.
In this work, a new chemiluminescence (CL) system of Co-Fe prussian blue analogs nanocubes (Co-Fe PBA NCs) that can catalyze luminol to produce strong CL in the absence of HO was established. Co-Fe PBA NCs have the property of oxidase-like activity, and it can catalyze the generation of active oxygen radicals in a dissolved oxygen system. Since caffeic acid (CA) can remove reactive oxygen species in the system, a sensitive detection method for CA on a paper-based chip was developed. Under the optimal conditions, this method showed a good linear response to CA in the range of 10 - 800 ng mL with a limit of 3 ng mL. The proposed method had been used for the determination of CA in tea samples. The results may open a new avenue for the catalytic property on luminol CL system without extra oxidants.
在这项工作中，建立了一种新的化学发光（CL）体系，即钴铁普鲁士蓝类似物纳米立方（Co-Fe PBA NCs），它可以在没有 HO 的情况下催化鲁米诺产生强 CL。Co-Fe PBA NCs 具有氧化酶样活性，它可以在溶解氧体系中催化活性氧自由基的生成。由于咖啡酸（CA）可以清除体系中的活性氧物种，因此开发了一种基于纸基芯片的 CA 敏感检测方法。在最佳条件下，该方法对 10-800ng/mL 范围内的 CA 表现出良好的线性响应，检出限为 3ng/mL。该方法已用于茶叶样品中 CA 的测定。该结果可能为无需额外氧化剂的鲁米诺 CL 体系的催化性能开辟新途径。
