采用超高效液相色谱-高分辨质谱法分析蔓越莓膳食补充剂中的酚类成分
Analysis of Phenolic Compositions in Cranberry Dietary Supplements using UHPLC-HRMS.
作者信息
Wang Yifei, Harrington Peter de B, Chen Pei
机构信息
U.S. Department of Agriculture, Agricultural Research Service, Beltsville Human Nutrition Research Center, Food Composition and Methods Development Laboratory, Beltsville, MD, US 20705.
Center for Intelligent Chemical Instrumentation, Department of Chemistry & Biochemistry, Ohio University, Athens, Ohio, 45701.
出版信息
J Food Compost Anal. 2020 Mar;86. doi: 10.1016/j.jfca.2019.103362. Epub 2019 Nov 9.
The potential human health benefits of American cranberry ( Ait.) leads to the popularity of its dietary supplements in the U.S. market. However, the qualities of the cranberry dietary supplements (CDSs) have never been carefully evaluated. In this study, the phenolic components in ten different CDSs were analyzed using ultra-performance liquid chromatography high-resolution mass spectrometry (UHPLC-HRMS). The study found quercetin and myricetin aglycones in most CDSs, but not in cranberry fruits, despite otherwise similar phenolic profiles between CDS and cranberry fruits in general. One supplement with high levels of B-type proanthocyanidins and non-cranberry flavonol rutin was determined to be adulterated by other botanical extracts. The CDSs only possessed 4% to 11% of the phenolic contents comparing to their claimed fresh cranberry equivalents, emphasizing the urgency of standardized product quality control and labelling for CDS manufacture and marketing.
美国蔓越莓（Ait.）对人体健康的潜在益处使得其膳食补充剂在美国市场广受欢迎。然而，蔓越莓膳食补充剂（CDS）的质量从未得到过仔细评估。在本研究中，使用超高效液相色谱高分辨率质谱法（UHPLC-HRMS）分析了十种不同CDS中的酚类成分。研究发现，大多数CDS中含有槲皮素和杨梅素苷元，但蔓越莓果实中却没有，尽管CDS和蔓越莓果实在总体酚类谱上其他方面相似。一种含有高水平B型原花青素和非蔓越莓黄酮醇芦丁的补充剂被确定掺有其他植物提取物。与所宣称的新鲜蔓越莓等效物相比，CDS仅含有4%至11%的酚类成分，这凸显了对CDS生产和销售进行标准化产品质量控制和标签标注的紧迫性。
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