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伴有咽后受累的非典型复发性川崎病:病例报告及文献综述

Atypical recurrent Kawasaki disease with retropharyngeal involvement: A case study and literature review.

作者信息

Cason Rachel K, Ponniah Umakumaran P, Makil Elizabeth S, Niu Mary C

机构信息

Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina, USA.

出版信息

Ann Pediatr Cardiol. 2020 Jul-Sep;13(3):244-247. doi: 10.4103/apc.APC_89_19. Epub 2020 Jun 11.

DOI:10.4103/apc.APC_89_19
PMID:32863663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7437624/
Abstract

Kawasaki disease (KD) is a systemic inflammatory condition primarily affecting young children. We present an adolescent male with two episodes of complete KD between the age of 2 and 14 years. At age 14, he presented with findings suggestive of a retropharyngeal abscess. This was later determined to be a recurrence of KD, diagnosed after the development of coronary artery aneurysms. Our case reinforces the role of maintaining a high index of suspicion for KD, both in patients with prior KD episodes and in those with persistent fever who do not fulfill the diagnostic criteria for typical KD. This is particularly important for patients presenting with atypical symptoms not commonly associated with KD, such as inflammation of the retropharyngeal and parapharyngeal spaces.

摘要

川崎病(KD)是一种主要影响幼儿的全身性炎症性疾病。我们报告一名青春期男性,在2岁至14岁之间发生了两次完全性KD发作。14岁时,他出现了提示咽后脓肿的症状。后来确定这是KD的复发,在冠状动脉瘤形成后确诊。我们的病例强化了对KD保持高度怀疑的重要性,无论是在既往有KD发作的患者中,还是在那些持续发热但不符合典型KD诊断标准的患者中。这对于表现出与KD通常无关的非典型症状的患者尤为重要,例如咽后和咽旁间隙炎症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d7/7437624/08e3e41d0134/APC-13-244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d7/7437624/f7e45dc0f6e7/APC-13-244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d7/7437624/08e3e41d0134/APC-13-244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d7/7437624/f7e45dc0f6e7/APC-13-244-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d7/7437624/08e3e41d0134/APC-13-244-g002.jpg

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本文引用的文献

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Deep Neck Space Involvement of Kawasaki Disease in the US: A Population-Based Study.川崎病累及美国颈部深部间隙:一项基于人群的研究。
J Pediatr. 2019 Dec;215:118-122. doi: 10.1016/j.jpeds.2019.07.054. Epub 2019 Aug 30.
2
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association.川崎病的诊断、治疗和长期管理:美国心脏协会发布的一份面向医疗保健专业人员的科学声明。
Circulation. 2017 Apr 25;135(17):e927-e999. doi: 10.1161/CIR.0000000000000484. Epub 2017 Mar 29.
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Nationwide surveys show that the incidence of recurrent Kawasaki disease in Japan has hardly changed over the last 30 years.
全国性调查显示,在过去30年里,日本川崎病复发的发病率几乎没有变化。
Acta Paediatr. 2017 May;106(5):796-800. doi: 10.1111/apa.13773. Epub 2017 Feb 26.
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Recurrent Kawasaki disease: USA and Japan.复发性川崎病:美国和日本。
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Development of Kawasaki disease in a patient with PFAPA.PFAPA患者发生川崎病
Pediatr Int. 2013 Dec;55(6):801-2. doi: 10.1111/ped.12225.
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A four-time-recurring typical complete Kawasaki syndrome successfully treated with intravenous immunoglobulin: a case report with literature review.四次复发典型完全川崎病经静脉注射免疫球蛋白成功治疗:病例报告并文献复习。
Rheumatol Int. 2013 Oct;33(10):2653-5. doi: 10.1007/s00296-012-2485-2. Epub 2012 Jul 20.
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Kawasaki disease at the extremes of the age spectrum.川崎病在年龄谱两端的表现。
Pediatrics. 2009 Sep;124(3):e410-5. doi: 10.1542/peds.2009-0099. Epub 2009 Aug 24.
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Recurrence of Kawasaki disease in an adult patient with cholecystitis.一名成年胆囊炎患者出现川崎病复发。
Ir Med J. 2007 Mar;100(3):400-1.
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Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association.川崎病的诊断、治疗及长期管理:美国心脏协会青少年心血管疾病理事会风湿热、心内膜炎及川崎病委员会为卫生专业人员发布的声明
Pediatrics. 2004 Dec;114(6):1708-33. doi: 10.1542/peds.2004-2182.
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Incidence survey of Kawasaki disease in 1997 and 1998 in Japan.1997年和1998年日本川崎病发病率调查
Pediatrics. 2001 Mar;107(3):E33. doi: 10.1542/peds.107.3.e33.