高剂量拉坦前列素治疗葡萄膜炎所致难治性低眼压
Uveitis-induced Refractory Ocular Hypotony Managed with High-dose Latanoprost.
作者信息
Ghassemi Fariba, Niyousha Mohammad Reza, Hassanpoor Narges, Khojasteh Hassan
机构信息
Retina & Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Retina & Vitreous Service, Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
J Ophthalmic Vis Res. 2020 Aug 6;15(3):408-411. doi: 10.18502/jovr.v15i3.7459. eCollection 2020 Jul-Sep.
PURPOSE
To report a case of refractory ocular hypotony due to chronic Behcet's disease with good response to high-dose topical latanoprost.
CASE REPORT
We present a 26-year-old man with a known history of Behcet's disease who developed decreasing vision and severe ocular hypotony that was refractory to multiple treatment modalities including subtenon triamcinolone acetonide, ibopamine, pars plana vitrectomy, and silicone oil injection. We decided to try high-dose topical latanoprost for the management of ocular hypotony based on recent reports. After six months, intraocular pressure (IOP) increased by 5 mm Hg, became stable at 7 mm Hg, and remained unchanged at month 24.
CONCLUSION
High-dose topical latanoprost could lead to significant increase in IOP in uveitis-induced refractory ocular hypotony.
目的
报告一例因慢性白塞病导致的难治性低眼压病例，该病例对高剂量局部用拉坦前列素反应良好。
病例报告
我们介绍一名26岁有白塞病病史的男性，其视力下降且眼压严重降低，对包括球周注射曲安奈德、异波帕明、玻璃体切割术及硅油注射在内的多种治疗方式均无反应。基于近期报道，我们决定尝试使用高剂量局部用拉坦前列素治疗低眼压。六个月后，眼压升高了5 mmHg，稳定在7 mmHg，并在24个月时保持不变。
结论
高剂量局部用拉坦前列素可使葡萄膜炎所致难治性低眼压患者的眼压显著升高。
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