Federal University of Acre (UFAC), Post-Graduation Program in Science, Innovation and Technology for the Amazonia, Rio Branco, Acre, Brazil; Federal University of Acre (UFAC), Post-Graduation Program in Biodiversity and Biotechnology of the Bionorte, Rio Branco, Acre, Brazil.
Federal University of Acre (UFAC), Post-Graduation Program in Science, Innovation and Technology for the Amazonia, Rio Branco, Acre, Brazil.
Int J Med Mushrooms. 2020;22(6):573-580. doi: 10.1615/IntJMedMushrooms.2020035050.
This study aimed to examine the antibacterial activity of extracts of Amazonian Agaricomycetes macrofungi. The sample comprised 168 specimen collected at the Zoobotanical Park of the Federal University of Acre (Brazil), of which 32 (19%) were isolated. Extracts of the 32 isolates and 28 Agaricomycetes basidiomata were prepared and tested for activity against Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, and Klebsiella pneumoniae bacteria, using the disc diffusion method. Of the 32 metabolite extracts of the isolated Basidiomycetes, 11 (34.4%) exhibited antibacterial activity especially against Gram-negative E. coli and K. pneumoniae bacteria, while of the 28 basidiomata extracts, 6 (21.4%) exhibited antibacterial activity mainly against the Gram-positive S. aureus bacteria. This study is the first to report the antibacterial activity of the Agaricomycetes species Coriolopsis caperata, Cyclomyces iodinus, Cymatoderma sp., Favolus tenuiculus, and Tyromyces cf. polyporoides, and contributes as the first investigation about the antibacterial potential of Basidiomycetes grown in Southwest Amazonia.
本研究旨在检验亚马逊伞菌目大型真菌提取物的抗菌活性。样本包括在巴西阿克里联邦大学动物植物园采集的 168 个标本，其中 32 个（19%）被分离。对 32 个分离物和 28 个伞菌目担子果的提取物进行了制备，并采用圆盘扩散法检测了它们对金黄色葡萄球菌、肺炎链球菌、大肠杆菌和肺炎克雷伯菌的活性。在分离出的担子菌的 32 种代谢物提取物中，有 11 种（34.4%）表现出抗菌活性，特别是对革兰氏阴性的大肠杆菌和肺炎克雷伯菌，而在 28 种担子果提取物中，有 6 种（21.4%）表现出抗菌活性，主要针对革兰氏阳性的金黄色葡萄球菌。本研究首次报道了 Coriolopsis caperata、Cyclomyces iodinus、Cymatoderma sp.、Favolus tenuiculus 和 Tyromyces cf. polyporoides 等 Agaricomycetes 物种的抗菌活性，并首次对生长在亚马逊西南部的 Basidiomycetes 的抗菌潜力进行了调查。
