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SARS-CoV-2 与登革热病毒的合并感染:临床挑战。

Co-infection of SARS-CoV-2 and dengue virus: a clinical challenge.

机构信息

HOME Hospital, Department of Infectious Diseases, Brasília, DF, Brazil.

HOME Hospital, Department of Infectious Diseases, Brasília, DF, Brazil.

出版信息

Braz J Infect Dis. 2020 Sep-Oct;24(5):452-454. doi: 10.1016/j.bjid.2020.07.008. Epub 2020 Aug 26.

DOI:10.1016/j.bjid.2020.07.008
PMID:32866435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7448779/
Abstract

Many regions of the world where dengue epidemics are seasonal are also facing the COVID-19 pandemic. This is a medical concern because both diseases are difficult to distinguish since they have similar clinical symptoms and laboratory findings, and because they have different clinical management. So far, co-infection of SARS-CoV-2 and dengue virus (DENV) has not been studied. Herein we report the first case of a patient with co-infection of COVID-19 and dengue. Both infections were simultaneously laboratory confirmed by positive RT-qPCR for SARS-CoV-2 and RT-qPCR for DENV, NS1, IgM and IgG antibody tests for dengue. The patient had a favorable clinical improvement, without severe symptoms. This case emphasize that, in pandemic era, having a diagnostic of one infection does not rule out the possibility of having another infection concomitantly. In addition, underscores the importance of an accurate and timely diagnosis to prevent the spread of COVID-19.

摘要

世界上许多发生登革热疫情的地区也面临着 COVID-19 大流行。这是一个医学关注点,因为这两种疾病难以区分,因为它们具有相似的临床症状和实验室发现,并且因为它们具有不同的临床管理。到目前为止,还没有研究 SARS-CoV-2 和登革热病毒(DENV)的合并感染。在此,我们报告了首例 COVID-19 和登革热合并感染的患者。两种感染均通过 SARS-CoV-2 的 RT-qPCR 和 DENV 的 RT-qPCR、登革热的 NS1、IgM 和 IgG 抗体检测同时实验室确认。患者的临床症状改善良好,没有出现严重症状。该病例强调,在大流行时代,对一种感染的诊断并不能排除同时存在另一种感染的可能性。此外,还强调了准确及时诊断的重要性,以防止 COVID-19 的传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/ee6e811f6d05/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/daba1b3a7ee4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/1a48acc52fa8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/ee6e811f6d05/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/daba1b3a7ee4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/1a48acc52fa8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a77c/9392109/ee6e811f6d05/gr3.jpg

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