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脊柱侧弯手术中同种异体骨与自体骨的比较

Allograft versus autograft bone in scoliosis surgery.

作者信息

Dodd C A, Fergusson C M, Freedman L, Houghton G R, Thomas D

机构信息

Nuffield Orthopaedic Centre, Oxford, England.

出版信息

J Bone Joint Surg Br. 1988 May;70(3):431-4. doi: 10.1302/0301-620X.70B3.3286656.

Abstract

The results of a study of the use of autograft versus allograft bone in the surgery of idiopathic adolescent scoliosis are presented. Two groups of patients, matched for age, sex, level and angle of curve, received bone grafts, 20 patients having autogenous bone from the iliac crest and the other 20 having donor bone from a bone bank. Both groups had otherwise identical posterior fusions and Harrington instrumentation. There was no difference between the two groups in a blind, radiographic assessment of bone graft mass at six months, nor in maintenance of the curve correction over the same period. No major operative complications nor failures of instrumentation were encountered. There was, however, a marked reduction in operative time and blood loss in the patients receiving donor bone and also a much lower incidence of late symptoms relating to the operative sites. We conclude that, even in the presence of adequate iliac crest, the use of bank bone is superior for grafting in idiopathic scoliosis surgery.

摘要

本文介绍了一项关于在特发性青少年脊柱侧弯手术中使用自体骨移植与同种异体骨移植的研究结果。两组年龄、性别、侧弯水平和角度相匹配的患者接受了骨移植,其中20例患者使用取自髂嵴的自体骨,另外20例患者使用来自骨库的供体骨。两组患者均接受了相同的后路融合术和哈林顿器械固定。在六个月时对骨移植量进行的盲法影像学评估中,两组之间没有差异,在同一时期的侧弯矫正维持情况方面也没有差异。未遇到重大手术并发症或器械故障。然而,接受供体骨的患者手术时间和失血量明显减少,与手术部位相关的晚期症状发生率也低得多。我们得出结论,即使有足够的髂嵴,在特发性脊柱侧弯手术中使用骨库骨进行移植更为优越。

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