Techniker Krankenkasse, Hamburg, Germany.
Department of Internal Medicine and Gastroenterology, Elisabeth-Krankenhaus Academic Hospital, University of Duisburg-Essen, Essen, Germany.
Endoscopy. 2020 Dec;52(12):1103-1110. doi: 10.1055/a-1206-0778. Epub 2020 Aug 31.
BACKGROUND : The efficacy and safety of over-the-scope (OTS) clips in the colon is limited. This study aimed to evaluate OTS clip use in the colon in routine colonoscopy.
Using administrative data from a large health insurance company, patients with OTS clip placement during colonoscopy were identified and analyzed by specific administrative codes. Indication for OTS clipping was analyzed, and follow-up was evaluated for surgical and repeat endoscopic interventions.
In 505 patients, indications for OTS clips were iatrogenic perforations (n = 80; Group A), polypectomy (n = 315; Group B), colonic bleeding (n = 51; Group C), and various underlying diseases (n = 59; Group D). In 11 Group A patients (13.8 %), surgical interventions occurred, mostly within 24 hours after clipping (n = 9), predominantly overstitching (n = 8). OTS clipping during polypectomy (Group B) was for complications (e. g. bleeding in 27 %) or was applied prophylactically. Only five patients required early surgery, three of whom had colorectal cancer. In four Group C patients (7.8 %), surgical resections were performed (persistent bleeding n = 1, colorectal cancer n = 2), while six patients underwent early repeat colonoscopy for recurrent bleeding. During further follow-up (days 11-30), 17 patients underwent resection for colonic neoplasms (n = 12) or persistent bleeding (n = 4), but only one case could be directly traced back to local OTS clip complication.
Colonic OTS clipping appears safe and effective in selected indications and complications in clinical routine but must be anatomically and technically feasible, avoiding overuse.
背景:在结肠中使用过内镜下全覆膜金属夹(OTS)的疗效和安全性有限。本研究旨在评估 OTS 夹在常规结肠镜检查中的应用。
使用来自大型健康保险公司的行政数据,通过特定的行政代码确定并分析接受结肠镜下 OTS 夹放置术的患者。分析 OTS 夹的适应证,并评估手术和重复内镜干预的随访情况。
在 505 例患者中,OTS 夹的适应证为医源性穿孔(n=80;A 组)、息肉切除术(n=315;B 组)、结肠出血(n=51;C 组)和各种基础疾病(n=59;D 组)。A 组 11 例患者(13.8%)接受了手术干预,主要发生在夹闭后 24 小时内(n=9),主要为缝合过紧(n=8)。在息肉切除术中(B 组)使用 OTS 夹是为了处理并发症(如出血 27%)或预防性使用。仅 5 例患者需要早期手术,其中 3 例患有结直肠癌。C 组 4 例患者(7.8%)接受了手术切除(持续出血 1 例,结直肠癌 2 例),而 6 例患者因再次出血行早期重复结肠镜检查。在进一步的随访(第 11-30 天)中,17 例患者因结肠肿瘤(n=12)或持续性出血(n=4)接受了切除,但只有 1 例可直接追溯到局部 OTS 夹并发症。
在临床常规中,选择性适应证和并发症的结肠 OTS 夹夹闭术安全且有效,但必须具有解剖学和技术可行性,避免过度使用。