2006-2016 年瑞典重症肌无力的流行病学。
Epidemiology of Myasthenia Gravis in Sweden 2006-2016.
机构信息
Department of Neuroscience, Clinical Neurophysiology, Uppsala University, Uppsala, Sweden.
出版信息
Brain Behav. 2020 Nov;10(11):e01819. doi: 10.1002/brb3.1819. Epub 2020 Sep 1.
INTRODUCTION
Reported incidence and prevalence rates of Myasthenia Gravis (MG) vary widely and are assumed to have increased over the last few decades. We conducted a nationwide register-based study on the current incidence and prevalence of MG and MG subgroups in Sweden.
METHODS
Data were acquired from four Swedish Health Registers in order to identify patients with MG. Incidence and prevalence rates were calculated for the years 2006-2016, using population numbers provided by Statistics Sweden.
RESULTS
In 2016, the incidence of MG in Sweden was 2.9 per 100,000 inhabitants (95% CI: 2.5-3.2/100,000) and the crude prevalence was 36.1 per 100,000 inhabitants (95% CI: 34.9-37.3). There was a significant increase in Myasthenia Gravis prevalence from 2006 to 2016. Prevalence rates of all MG subgroups but thymoma-associated MG increased over the same period of time.
CONCLUSIONS
The incidence and prevalence of Myasthenia Gravis have increased over time in Sweden, and the rates are high in comparison with other countries.
简介
重症肌无力 (MG) 的报告发病率和患病率差异很大，据推测在过去几十年中有所增加。我们在瑞典进行了一项基于全国登记的研究，以确定当前 MG 及 MG 亚组的发病率和患病率。
方法
为了识别患有 MG 的患者，我们从四个瑞典健康登记处获取了数据。发病率和患病率是根据瑞典统计局提供的人口数字，在 2006-2016 年期间计算得出的。
结果
2016 年，瑞典的 MG 发病率为每 10 万人中有 2.9 例（95%CI：2.5-3.2/100,000），粗患病率为每 10 万人中有 36.1 例（95%CI：34.9-37.3）。MG 的患病率从 2006 年到 2016 年显著增加。除胸腺瘤相关 MG 外，所有 MG 亚组的患病率均在同一时期增加。
结论
在瑞典，重症肌无力的发病率和患病率随时间推移而增加，与其他国家相比，其发病率较高。
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