Ishibashi Naoya, Maebayashi Toshiya, Nishimaki Haruna, Okada Masahiro
Department of Radiology, Nihon University School of Medicine, Tokyo, Japan
Department of Radiology, Nihon University School of Medicine, Tokyo, Japan.
In Vivo. 2020 Sep-Oct;34(5):2721-2725. doi: 10.21873/invivo.12093.
Computed tomography (CT) performed after radiation therapy (RT) is used to detect residual lymph node (LN) metastasis. Here, we investigated which LN parameters on pre- and post-RT CT images correlated with residual tumour in patients with head and neck cancer.
We enrolled 23 patients who received RT. A total of 50 LNs were evaluated. Correlations between quantitative and qualitative findings and residual tumours were evaluated.
The median patient age was 61 years. Thirty-one LNs were histologically confirmed to contain residual tumour. LNs with residual tumour had significantly longer short and long axes on post-RT CT images. A new finding of obscured margins after RT were significantly associated with the presence of residual tumour by univariate and multivariate analyses.
Comparison of qualitative, LN parameters on pre- and post-RT CT images may improve the detection of residual tumour in patients with suspected residual or recurrent LN metastasis.
放射治疗(RT)后进行的计算机断层扫描(CT)用于检测残留淋巴结(LN)转移。在此,我们研究了头颈部癌患者放疗前后CT图像上哪些LN参数与残留肿瘤相关。
我们纳入了23例接受放疗的患者。共评估了50个LN。评估了定量和定性结果与残留肿瘤之间的相关性。
患者中位年龄为61岁。31个LN经组织学证实含有残留肿瘤。有残留肿瘤的LN在放疗后CT图像上的短轴和长轴明显更长。放疗后边缘模糊这一新发现经单因素和多因素分析与残留肿瘤的存在显著相关。
比较放疗前后CT图像上定性的LN参数可能会提高对疑似残留或复发性LN转移患者残留肿瘤的检测。