Gao Li-Nan, Ge Lian-Gang, Zhu Ming-Zhe, Yao Xin-Xin
Department of Laboratory, Affiliated Hospital of Jilin Medical University.
Department of Radiotherapy, The Second People's Hospital of Jilin.
Medicine (Baltimore). 2020 Aug 14;99(33):e21667. doi: 10.1097/MD.0000000000021667.
This study will explore the association between tumor necrosis factor α (TNF-α) and uterine fibroids (UFs).
We will retrieve electronic databases in Cochrane Library, PUBMED, EMBASE, Web of Science, WANGFANG, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from inception to the present. All potential case-controlled studies investigating the association between TNF-α and UFs will be included in this study. Two researchers will independently select literature, appraise study quality, and extract outcome data. We will utilize a fixed-effects model or a random-effects model to synthesize outcome data. All data analysis will be performed by RevMan 5.3 software.
The present study will supply high-quality synthesis and/or descriptive analysis of the recent evidence to explore the association between TNF-α and UFs.
This study will exert evidence to determine whether or not TNF-α is associated with UFs.
INPLASY202070010.
本研究将探讨肿瘤坏死因子α（TNF-α）与子宫肌瘤（UFs）之间的关联。
我们将检索Cochrane图书馆、PUBMED、EMBASE、科学网、万方、中国生物医学文献数据库和中国知网等电子数据库，检索时间从建库至目前。所有调查TNF-α与UFs之间关联的潜在病例对照研究都将纳入本研究。两名研究人员将独立选择文献、评估研究质量并提取结果数据。我们将使用固定效应模型或随机效应模型来综合结果数据。所有数据分析将通过RevMan 5.3软件进行。
本研究将提供近期证据的高质量综合分析和/或描述性分析，以探讨TNF-α与UFs之间的关联。
本研究将为确定TNF-α是否与UFs相关提供证据。
INPLASY202070010。
