Department of Nuclear Medicine, Nanjing First Hospital, Nanjing Medical University, 68th Changle Road, Nanjing, 210006, China.
Department of Cardiothoracic Surgery, Nanjing First Hospital, Nanjing Medical University, 68th Changle Road, Nanjing, 210006, China.
J Cardiothorac Surg. 2020 Sep 1;15(1):233. doi: 10.1186/s13019-020-01271-3.
Pulmonary artery intimal sarcoma (PAIS) is a rare malignant tumor that was usually misdiagnosed as chronic pulmonary thromboembolism.
We previously reported a solitary fibrous tumor in the pulmonary artery presented with acute pulmonary embolism, which was identified by Tc-Galacto-RGD imaging. However, this patient had a recurrence in situ two-year after surgery, post-operative pathology revealed pulmonary artery intimal sarcoma. At one-year post-operation, F-FDG PET/CT was performed for exclusion of tumor metastasis, which showed FDG avid lesion in the T5, T10, and L5 vertebral bodies, as well as in bilateral ilium and right ischium.
This is the first longitudinal observation of a solitary fibrous tumor (SFT) development into a pulmonary artery intimal sarcoma (PAIS) and presented with multiple bone metastases.
肺动脉内膜肉瘤（PAIS）是一种罕见的恶性肿瘤，通常被误诊为慢性肺血栓栓塞症。
我们之前曾报道过一例肺动脉孤立性纤维瘤表现为急性肺栓塞，通过 Tc-Galacto-RGD 成像得以确诊。然而，该患者在手术后两年原位复发，术后病理显示为肺动脉内膜肉瘤。术后一年，进行 F-FDG PET/CT 检查以排除肿瘤转移，结果显示 T5、T10 和 L5 椎体以及双侧髂骨和右侧坐骨存在 FDG 摄取病灶。
这是首例孤立性纤维瘤（SFT）发展为肺动脉内膜肉瘤（PAIS）并伴有多处骨转移的纵向观察。
