Increases of neuropeptide Y-like immunoreactivity in plasma during insulin-induced hypoglycemia in man.
作者信息
Takahashi K, Mouri T, Murakami O, Itoi K, Sone M, Ohneda M, Nozuki M, Yoshinaga K
机构信息
Second Department of Internal Medicine, Tohoku University School of Medicine, Miyagi, Japan.
出版信息
Peptides. 1988 Mar-Apr;9(2):433-5. doi: 10.1016/0196-9781(88)90281-1.
PMID:3287359
Abstract
Neuropeptide Y-like immunoreactivity (NPY-LI) in plasma during insulin-induced hypoglycemia was measured in 4 healthy male volunteers. Plasma NPY-LI increased from 167 +/- 11 pg/ml to 247 +/- 25 pg/ml 30 min after the administration of insulin (0.1 U/kg body weight IV), reached the maximum (296 +/- 6 pg/ml) 45 min after the insulin, and then decreased. These results suggest that NPY is released into the systemic circulation during insulin-induced hypoglycemia in man.
摘要
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