Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Iran.
Tabriz University of Medical Sciences, Iran.
Ethiop J Health Sci. 2020 May;30(3):397-408. doi: 10.4314/ejhs.v30i3.11.
Blood transfusion is a life-saving procedure; millions of lives are saved each year. However, blood transfusions are associated with certain risks that can lead to adverse consequences. This study aimed to survey the prevalence and trend of hepatitis B virus (HBV), hepatitis C virus (HCV), and Human immunodeficiency virus (HIV) among blood donors of Fars province, Iran (2006-2018).
This retrospective cross-sectional study was conducted by reviewing the records of the blood transfusion organization of Fars province. A total of 1952478 blood units were screened for transfusion-transmitted infections (TTIs). Then, data were entered into SPSS software (Negare. version 25). Chi-square test was used to compare the sof TTIs among blood donors. Chisquare test for trend was used to analyze the variations in trends of TTIs during this period. Finally, p-values less than 0.05 were considered statistically significant. GraphPad Prism software was used for the depiction of the graphs.
Among the 1952478 blood donations within the 13-years, 4479(0.229 %) of donors were HBsAg, HCV Ab, and HIV Ag-Ab positive. The seroprevalence of HBV, HCV, and HIV was 2684(0.137%), 1703(0.087 %), and 92(0.0047%), respectively.
The current study showed that the overall prevalence of TTIs among blood donors was low and had a descending trend over the years of study.
输血是一种救命的程序；每年都有数百万人因此获救。然而，输血也存在一定的风险，可能导致不良后果。本研究旨在调查伊朗法尔斯省（2006-2018 年）献血者中乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和人类免疫缺陷病毒（HIV）的流行率和趋势。
本回顾性横断面研究通过查阅法尔斯省输血组织的记录进行。共筛查了 1952478 个血单位的输血传播感染（TTIs）。然后，数据被输入到 SPSS 软件（Negare.版本 25）中。卡方检验用于比较献血者之间的 TTIs。卡方检验趋势用于分析该期间 TTIs 趋势的变化。最后，p 值小于 0.05 被认为具有统计学意义。GraphPad Prism 软件用于绘制图形。
在 13 年的 1952478 个献血中，有 4479 名（0.229%）献血者 HBsAg、HCV Ab 和 HIV Ag-Ab 阳性。HBV、HCV 和 HIV 的血清流行率分别为 2684（0.137%）、1703（0.087%）和 92（0.0047%）。
本研究表明，献血者 TTIs 的总体流行率较低，且在研究期间呈下降趋势。
