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[大规模乳腺钼靶筛查。降低乳腺癌死亡率的一种手段?]

[Mass mammography screening. A means of reducing mortality in breast cancer?].

作者信息

Bauer M, Schulz-Wendtland R, von Fournier D

机构信息

Abteilung Gynäkologische Radiologie, Radiologischen Klinik der Universität Freiburg.

出版信息

Radiologe. 1988 Mar;28(3):95-102.

PMID:3287445
Abstract

The already high and still rising mortality rate for breast carcinoma continues to represent a serious problem, especially since neither surgical treatment nor radiotherapy has a significant influence on the prognosis of the disease. Mammography has made it possible to diagnose small and minute carcinomas of the breast before they become clinically symptomatic. Lymph node involvement is histologically confirmed in approximately 20% of breast carcinomas detected by mammography, as opposed to roughly 50% of the tumors diagnosed clinically. Further, in randomized studies mammoscreening was shown to reduce the mortality rates by 30% to 40%. Mammoscreening thus appears to be the only means of diminishing the mortality rate for breast carcinoma.

摘要

乳腺癌已然居高不下且仍在上升的死亡率一直是个严重问题,尤其是因为手术治疗和放射治疗对该疾病的预后均无显著影响。乳腺钼靶摄影使得在乳腺癌出现临床症状之前就能诊断出微小癌。经乳腺钼靶摄影检测出的乳腺癌中,约20%在组织学上证实有淋巴结受累,而临床诊断的肿瘤这一比例约为50%。此外,在随机研究中,乳腺钼靶筛查显示可将死亡率降低30%至40%。因此,乳腺钼靶筛查似乎是降低乳腺癌死亡率的唯一手段。

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