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印度尼西亚泗水市听力门诊先天性风疹综合征概况

Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia.

作者信息

Rosalina Elsa, Purnami Nyilo

机构信息

Faculty of Medicine, Universitas Airlangga, Surabaya.

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, Indonesia.

出版信息

Infect Dis Rep. 2020 Jul 6;12(Suppl 1):8762. doi: 10.4081/idr.2020.8762. eCollection 2020 Jul 7.

Abstract

Congenital Rubella Syndrome (CRS) consists of hearing impairment, ophthalmology abnormalities, and congenital heart disease in children, resulting from rubella infection during pregnancy. Rubella vaccine has been implemented as national immunization program in Indonesia since 2017, and needed to be evaluated. This study aimed to report the CRS patients' profile of Audiology Outpatient Clinic in Surabaya. A descriptive study from patient's medical record was conducted in Dr. Soetomo Hospital Surabaya from January 2016 to December 2017. CRS was categorized using World Health Organization classification. Suspected infants with CRS burden were assessed by Otoacoustic Emission and rubella antibody test. Ninety five infants suspected with CRS classified as laboratory- confirmed CRS (58.95%), clinically confirmed CRS (15.79%), and discarded CRS (25.26%). Clinical manifestations included combination of congenital heart disease and hearing impairment (17.89%), congenital heart disease, ophthalmology abnormalities, and hearing impairment (16.84%), and hearing impairment and ophthalmology abnormalities (13.68%). The data show a high burden of CRS in Surabaya. These implies the urgent need for national rubella immunization program.

摘要

先天性风疹综合征(CRS)是指儿童因孕期感染风疹而出现听力障碍、眼科异常和先天性心脏病。自2017年起,风疹疫苗已在印度尼西亚作为国家免疫规划实施,需要对其进行评估。本研究旨在报告泗水听力门诊先天性风疹综合征患者的情况。2016年1月至2017年12月,在泗水苏托莫医院对患者病历进行了描述性研究。先天性风疹综合征采用世界卫生组织分类法进行分类。对疑似患有先天性风疹综合征的婴儿通过耳声发射和风疹抗体检测进行评估。95名疑似先天性风疹综合征的婴儿被分类为实验室确诊的先天性风疹综合征(58.95%)、临床确诊的先天性风疹综合征(15.79%)和排除的先天性风疹综合征(25.26%)。临床表现包括先天性心脏病合并听力障碍(17.89%)、先天性心脏病、眼科异常和听力障碍(16.84%)以及听力障碍和眼科异常(13.68%)。数据显示泗水先天性风疹综合征负担较高。这意味着迫切需要实施国家风疹免疫规划。

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