IanoȘi Nicolae Gabriel, Neagoe Carmen Daniela, Tutunaru Cristina Violeta, CĂlbureanu-Popescu Madalina Xenia, DrĂguȘin Liviu, GÎngeoveanu Gabriel, Farmazon Anca, PĂun Ion, IanoȘi Simona Laura
Surgical Department, Medical Center Dr. Ianoși, Craiova, Romania.
Internal Medical Department, Medical Center Dr. Ianoși, University of Medicine and Pharmacy of Craiova, Romania.
Curr Health Sci J. 2020 Apr-Jun;46(2):141-149. doi: 10.12865/CHSJ.46.02.07. Epub 2020 Jun 30.
The treatment of leg telangiectasias could be done with liquid sclerotherapy or Nd:YAG laser. We evaluated randomly, in a simple blind, the efficacy of the treatment with 0,5% polidocanol (POL-0,5), 1% polidocanol (POL-1) and Nd:YAG laser (LAS) on 132 patient (264 limbs) with telangiectasia of the lower limbs with less than 2mm diameter (C1EAP). The main objective was to evaluate the efficacy of the sclerotherapy (chemical compared with Nd:YAG-LAS). Secondary objectives were: possible major complications (deep thrombosis, severe burns, ischemic complications, etc.), the percentage of the local complications, the cosmetic aspect-evaluated by both the patient and the doctor and the grade of discomfort of the patient during and after the procedure. Comparing the treatment with Nd:YAG laser (LAS), polidecanol-0.5% (POL-0.5), polidecanol 1% (POL-1), it was noticed that telangiectasias smaller than 1mm led to good and very good results in all the cases treated with Nd:YAG laser and the same outcome was obtained in one third of the subjects treated with POL-0.5, vs. 47.81% of patients treated with POL-1. When telangiectasias were larger than 1mm diameter, good and very good results occurred in 86.36% of patients treated with LAS and 100% of the cases treated with POL-0.5 and POL-1. In conclusion, we consider that leg telangiectasias can be treated with good results using Nd:YAG laser or sclerotherapy with polidocanol, Nd:YAG laser being reccomended for telangiectasia under than 1 mm diameter while sclerotherapy in larger vessels.
钇铝石榴石激光。我们以简单盲法对132例（264条肢体）直径小于2mm的下肢毛细血管扩张症（C1EAP）患者随机评估了0.5%聚多卡醇（POL - 0.5）、1%聚多卡醇（POL - 1）和钕:钇铝石榴石激光（LAS）治疗的疗效。主要目的是评估硬化疗法（化学疗法与钕:钇铝石榴石激光相比）的疗效。次要目的包括：可能的主要并发症（深部血栓形成、严重烧伤、缺血性并发症等）、局部并发症的发生率、患者和医生评估的美容效果以及患者在治疗期间和治疗后的不适程度。比较钕:钇铝石榴石激光（LAS）、0.5%聚多卡醇（POL - 0.5）、1%聚多卡醇（POL - 1）的治疗情况，发现直径小于1mm的毛细血管扩张症在所有接受钕:钇铝石榴石激光治疗的病例中均取得了良好和非常好的效果，在接受POL - 0.5治疗的患者中有三分之一取得了相同的结果，而接受POL - 1治疗的患者中有47.81%取得了相同结果。当毛细血管扩张症直径大于1mm时，接受LAS治疗的患者中有86.36%取得了良好和非常好的效果，接受POL - 0.5和POL - 1治疗的病例中有100%取得了良好和非常好的效果。总之，我们认为使用钕:钇铝石榴石激光或聚多卡醇硬化疗法治疗腿部毛细血管扩张症均可取得良好效果，对于直径小于1mm的毛细血管扩张症推荐使用钕:钇铝石榴石激光，而对于较大血管则推荐使用硬化疗法。
