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系统性硬化症相关间质性肺疾病患者的鸟分枝杆菌复合群感染:一例报告

Mycobacterium avium complex infection in a patient with systemic sclerosis- associated interstitial lung disease: A case report.

作者信息

Campo-Rivera Natalia, Castillo Delgado Raul, Rodriguez Florez Augusto

机构信息

Internal Medicine Department, Universidad Libre, Cali, Colombia.

Pathology Department, Centro Médico Imbanaco, Cali, Colombia.

出版信息

Respir Med Case Rep. 2020 Aug 6;31:101184. doi: 10.1016/j.rmcr.2020.101184. eCollection 2020.

Abstract

We describe a case of a 65-year-old male with recently diagnosed diffuse cutaneous systemic sclerosis associated with usual interstitial pneumonia and pulmonary hypertension. Patient presented to the emergency department complaining of low-grade fever, increased sputum production, progressive dyspnea and weight loss. High-resolution computed tomography scan showed multifocal bronchiectasis with multiple small nodules. Bronchoalveolar lavage culture was positive for Antimicrobial treatment was started which improved respiratory symptoms. One month after the initiation of antibiotics, cyclophosphamide therapy was started with adequate tolerance.

摘要

我们描述了一例65岁男性患者,近期诊断为弥漫性皮肤型系统性硬化症,伴有普通型间质性肺炎和肺动脉高压。患者因低热、痰液增多、进行性呼吸困难和体重减轻就诊于急诊科。高分辨率计算机断层扫描显示多灶性支气管扩张伴多个小结节。支气管肺泡灌洗培养对抗菌治疗呈阳性反应,开始抗菌治疗后呼吸道症状有所改善。抗生素治疗开始一个月后,开始使用环磷酰胺治疗,患者耐受性良好。

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