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资源有限环境下口服亚甲蓝和维生素C治疗硝基苯中毒:一例报告

Management of nitrobenzene poisoning with oral methylene blue and vitamin C in a resource limited setting: A case report.

作者信息

Shrestha Ninadini, Karki Bipin, Shrestha Pramesh Sunder, Gami Rupesh, Acharya Subhash Prasad, Acharya Santosh

机构信息

Department of Anaesthesia, Maharajgunj Medical Campus, Institute of Medicine, GPO Box- 1524, Maharajgunj, Kathmandu, Nepal.

Department of Critical Care Medicine, Om Hospital and Research Center Pvt Ltd, GPO Box- 13494, Chabahil, Kathmandu, Nepal.

出版信息

Toxicol Rep. 2020 Aug 15;7:1008-1009. doi: 10.1016/j.toxrep.2020.08.012. eCollection 2020.

Abstract

Nitrobenzene can cause life threatening methaemoglobinemia. Its management includes the use of intravenous methylene blue to reduce the iron moiety from its ferric to ferrous state. Due to unavailability of intravenous preparation, enteral methylene blue was used in our case. This case report is to highlight that even oral preparations can be successfully used in a resource limited setting where often intravenous preparations are unavailable.

摘要

硝基苯可导致危及生命的高铁血红蛋白血症。其治疗方法包括使用静脉注射亚甲蓝,将铁部分从三价还原为二价状态。由于无法获得静脉制剂,我们的病例中使用了肠内亚甲蓝。本病例报告旨在强调,在资源有限的环境中,即使没有静脉制剂,口服制剂也可成功使用,而在这种环境中静脉制剂往往难以获得。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38b1/7451750/6897ea49993c/ga1.jpg

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