一例因硝基苯中毒导致的严重高铁血红蛋白血症致死病例。
A fatal case of severe methaemoglobinemia due to nitrobenzene poisoning.
作者信息
Gupta Alok, Jain Nirdesh, Agrawal Avinash, Khanna Arjun, Gutch Manish
机构信息
Department of Internal Medicine, CSM Medical University, Lucknow, Uttar Pradesh, India.
出版信息
BMJ Case Rep. 2011 Oct 4;2011:bcr0720114431. doi: 10.1136/bcr.07.2011.4431.
An acute poisoning with nitrobenzene presenting as methaemoglobinemia is an uncommon medical emergency. A young girl with nitrobenzene induced methaemoglobinaemia died despite use of mechanical ventilator, administration of oral methylene blue and parenteral ascorbic acid. Here author highlights the rare occurrence of such cases, methaemoglobin induced severe oxidative stress, unexplained splenomegaly and leucocytosis and the ineffectivity of oral methylene blue and other supportive measures in evading death due to nitrobenzene poisoning.
以高铁血红蛋白血症为表现的急性硝基苯中毒是一种罕见的医疗急症。一名患有硝基苯诱导的高铁血红蛋白血症的年轻女孩，尽管使用了机械通气、口服亚甲蓝和肠外给予维生素C，仍不幸死亡。在此，作者强调了此类病例的罕见性、高铁血红蛋白诱导的严重氧化应激、不明原因的脾肿大和白细胞增多，以及口服亚甲蓝和其他支持措施在避免硝基苯中毒导致死亡方面的无效性。
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