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抑郁症状是死亡的独立危险因素。

Depressive symptoms as an independent risk factor for mortality.

机构信息

Programa de Pós-Graduação em Ciências da Reabilitação, Universidade Federal de Santa Catarina (UFSC), Araranguá, SC, Brazil.

Programa de Pós-Graduação em Saúde Coletiva, Universidade Federal do Maranhão (UFMA), São Luís, MA, Brazil.

出版信息

Braz J Psychiatry. 2021 May-Jun;43(3):247-253. doi: 10.1590/1516-4446-2019-0749.

DOI:10.1590/1516-4446-2019-0749
PMID:32876136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8136396/
Abstract

OBJECTIVE

To evaluate the relationship between presence of depressive symptoms and risk of death in older adults residing in a municipality in Southern Brazil.

METHODS

Between 2009 and 2014, 1,391 people participated in the EpiFloripa Aging Cohort Study, a population-based longitudinal study. Depressive symptoms were assessed through the Geriatric Depression Scale. The initial time was considered the age at the first interview, and the end time, the age at the last contact or death. Cox regression models were used to estimate the mortality risk associated with depressive symptoms, adjusted by sex, education, income, paid work, smoking status, alcohol consumption, morbidities, medication use, physical activity, disability, cognitive impairment, and body mass index.

RESULTS

The prevalence of depressive symptoms was 23.5% (95%CI 20.4-26.9). On crude analysis, the risk of mortality was 1.86 (95%CI 1.35-2.55) for individuals with depressive symptoms; in adjusted models, the risk of mortality was 1.67 (95%CI 1.15-2.40).

CONCLUSION

Depressive symptoms are an independent risk factor for mortality in older Brazilian adults. Our findings highlight the importance of screening this population for depression and the practice of preventive actions.

摘要

目的

评估巴西南部一市老年人群中存在抑郁症状与死亡风险的关系。

方法

2009 年至 2014 年期间,有 1391 人参加了 EpiFloripa 老龄化队列研究,这是一项基于人群的纵向研究。抑郁症状通过老年抑郁量表进行评估。初始时间被视为第一次访谈时的年龄,结束时间被视为最后一次联系或死亡时的年龄。使用 Cox 回归模型来估计与抑郁症状相关的死亡风险,调整因素包括性别、教育、收入、有薪工作、吸烟状况、饮酒状况、疾病、用药情况、身体活动、残疾、认知障碍和体重指数。

结果

抑郁症状的患病率为 23.5%(95%CI 20.4-26.9)。在粗分析中,有抑郁症状的个体的死亡风险为 1.86(95%CI 1.35-2.55);在调整模型中,死亡风险为 1.67(95%CI 1.15-2.40)。

结论

抑郁症状是巴西老年成年人死亡的独立危险因素。我们的研究结果强调了对该人群进行抑郁筛查和采取预防措施的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7668/8136396/8bb82c856e5c/bjp-43-03-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7668/8136396/8bb82c856e5c/bjp-43-03-247-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7668/8136396/8bb82c856e5c/bjp-43-03-247-g001.jpg

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