酵母：现代生物学的实验生物体。
Yeast: an experimental organism for modern biology.
作者信息
Botstein D, Fink G R
机构信息
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
出版信息
Science. 1988 Jun 10;240(4858):1439-43. doi: 10.1126/science.3287619.
PMID:3287619
Abstract
The yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have become popular and successful model systems for understanding eukaryotic biology at the cellular and molecular levels. The reasons for this success are experimental tractability, especially in applying classical and molecular genetic methods to associate genes with proteins and functions within the cell.
摘要
酿酒酵母（Saccharomyces cerevisiae）和粟酒裂殖酵母（Schizosaccharomyces pombe）已成为在细胞和分子水平上理解真核生物生物学的流行且成功的模式系统。取得这一成功的原因在于实验的易操作性，特别是在应用经典和分子遗传学方法将基因与细胞内的蛋白质及功能联系起来方面。
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