Dipartimento di Scienze Chimiche, Università degli Studi di Padova, Via Marzolo 1, 35131 Padova, Italy.
INSTM, UdR di Padova, Via Marzolo 1, 35131 Padova, Italy.
ACS Appl Mater Interfaces. 2020 Sep 30;12(39):44074-44087. doi: 10.1021/acsami.0c13150. Epub 2020 Sep 16.
The room-temperature controlled crystallization of monodispersed ZnS nanoparticles (average size of 5 nm) doped with luminescent ions (such as Mn, Eu, Sm, Nd, and Yb) was achieved via a microfluidic approach. The preparation did not require any stabilizing ligands or surfactants, minimizing potential sources of impurities. The synthesized nanomaterials were characterized from a structural (XRD and XAS at lanthanide L edges), morphological (TEM), and compositional (XPS, ICP-MS) perspective, giving complementary information on the materials' features. In view of potential applications in the field of optical bioimaging, the optical emission properties of the doped nanoparticles were assessed, and samples showed strong luminescent properties while being less affected by self-quenching mechanisms. Furthermore, cytotoxicity experiments were conducted, showing no negative effects and evidencing the appeal of the synthesized materials for potential applications in the field of optical bioimaging.
通过微流控方法实现了室温控制下的单分散 ZnS 纳米粒子（平均尺寸为 5nm）的结晶，该纳米粒子掺杂了发光离子（如 Mn、Eu、Sm、Nd 和 Yb）。该制备过程不需要任何稳定剂或表面活性剂，最大限度地减少了潜在的杂质来源。通过结构（XRD 和镧系元素 L 边的 XAS）、形态（TEM）和组成（XPS、ICP-MS）对合成的纳米材料进行了表征，为材料的特性提供了互补信息。鉴于在光学生物成像领域的潜在应用，评估了掺杂纳米粒子的光学发射特性，结果表明，这些样品具有较强的发光性能，且受自猝灭机制的影响较小。此外，进行了细胞毒性实验，结果表明没有负面效应，证明了所合成材料在光学生物成像领域的潜在应用的吸引力。
