Netsky M G
Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.
Surg Neurol. 1988 Jun;29(6):477-83. doi: 10.1016/0090-3019(88)90144-9.
Reports of epidermoid tumors from 1965 through 1986 were reviewed with emphasis on new and unusual findings. Clinical data considered were rapid onset, rare symptoms, size and rate of growth, and complications. Uncommon locations included multiple sites in one patient and the anterior fontanelle. The radiologic data from computed tomography were the main contributors to diagnosis. An immunohistochemical test disclosed that cells of craniopharyngiomas are keratin-positive. Histologically benign epidermoids can behave as highly malignant tumors, and can become carcinomatous. Postoperative results for benign tumors were often excellent. Evidence was presented of the close relation among epidermoid and dermoid tumor, craniopharyngioma, ameloblastoma (adamantinoma), Rathke's cleft cyst, and aural cholesteatoma.
回顾了1965年至1986年期间表皮样肿瘤的报告，重点关注新的和不寻常的发现。所考虑的临床数据包括发病迅速、罕见症状、大小和生长速度以及并发症。不常见的部位包括同一患者的多个部位和前囟门。计算机断层扫描的放射学数据是诊断的主要依据。免疫组织化学检测显示颅咽管瘤细胞角蛋白呈阳性。组织学上良性的表皮样肿瘤可表现为高度恶性肿瘤，并可发生癌变。良性肿瘤的术后结果通常良好。有证据表明表皮样和皮样肿瘤、颅咽管瘤、成釉细胞瘤（造釉细胞瘤）、拉克囊囊肿和耳胆脂瘤之间关系密切。
