Department of Neurological Sciences, Christian Medical College, Vellore, India.
Department of Pathology, Christian Medical College, Vellore, India.
Acta Neurochir (Wien). 2023 Jun;165(6):1671-1674. doi: 10.1007/s00701-023-05597-4. Epub 2023 Apr 24.
Proliferating trichilemmal tumors (PTT) are rare benign lesions that predominantly occur in elderly women and usually affect the scalp. They originate from the outer root sheath of hair shafts and have trichilemmal differentiation on histopathological examination. Compared to trichilemmal cysts, PTTs show increased cell proliferation and variable cytological atypia. We report the first case of a patient with an intracranial PTT in the posterior fossa. The clinicoradiological presentation and surgical management of the patient as well as the possible pathogenesis of this tumor are discussed.
增殖性毛鞘瘤（PTT）是一种罕见的良性病变，主要发生于老年女性，通常累及头皮。它起源于毛干的外根鞘，组织病理学检查显示毛鞘分化。与毛鞘囊肿相比，PTT 表现为细胞增殖增加和不同程度的细胞学异型性。我们报告首例发生于颅后窝的颅内 PTT。讨论了患者的临床影像学表现、手术治疗以及该肿瘤的可能发病机制。
