Stem Cells and Regenerative Medicine Research Department, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
J Eval Clin Pract. 2021 Aug;27(4):799-808. doi: 10.1111/jep.13472. Epub 2020 Sep 2.
RATIONALE, AIMS, AND OBJECTIVES: Cell-based therapeutics are among the latest advances in health care technologies. The rapid evolution of stem cell science in Iran has necessitated the application of scientific achievements in clinical settings. However, various issues hindered their translation, in particular, impediments in the interactions of basic stem cell scientists and clinicians. We highlighted the impediments in the interactions of stem cell scientists and physicians involved in the opinion of professionals from both groups.
This qualitative research was conducted with thematic analysis, performed by purposive sampling. Thirty-two distinguished stem cell scientists and clinicians were interviewed to identify their perspectives on this matter. MAXQDA 2018 was used to classify the axial codes based on factors related to communications inefficiencies. The analysis of coded data recognized 18 subthemes and six major themes.
Central themes include different registers of the two parties, counterproductive clusters hampered networking, external communication barriers, the competition to access resources, leadership conflicts, and the dissatisfaction of stakeholders with their share.
Most of the impediments were seemingly global, for example, the incoherent medical and basic science educational systems, the vulnerable career path of physician-scientists, and an increasing tendency towards overspecialization. However, some local specific issues were also described, for example, limited funding opportunities and the negative impacts of the division of medical education from the ministry of science, research, and technology in Iran. Proposed interventions include the reinforcement of physician-scientist programs, designing a distributed leadership model, and bringing back the scientific integrity to higher education in Iran.
背景、目的和目标:细胞治疗是医疗保健技术的最新进展之一。伊朗干细胞科学的快速发展使得有必要将科学成果应用于临床环境中。然而,各种问题阻碍了它们的转化,特别是基础干细胞科学家和临床医生之间互动的障碍。我们强调了参与该领域的干细胞科学家和医生之间互动的障碍,这是根据来自这两个群体的专业人士的意见得出的。
本定性研究采用主题分析进行,通过目的抽样进行。采访了 32 位杰出的干细胞科学家和临床医生,以了解他们对这一问题的看法。使用 MAXQDA 2018 根据与沟通效率低下相关的因素对轴向代码进行分类。对编码数据的分析识别出 18 个副标题和 6 个主要主题。
核心主题包括双方的不同登记、产生反效果的集群阻碍网络、外部沟通障碍、获取资源的竞争、领导冲突以及利益相关者对其份额的不满。
大多数障碍似乎是全球性的,例如,医学和基础科学教育系统不协调、医师科学家的职业道路脆弱以及过度专业化的趋势增加。然而,也描述了一些当地的具体问题,例如,有限的资金机会以及伊朗将医学教育从科学、研究和技术部分离的负面影响。拟议的干预措施包括加强医师科学家计划、设计分布式领导模式以及恢复伊朗高等教育的科学完整性。