Dis Model Mech. 2011 Jul;4(4):423-6. doi: 10.1242/dmm.008177.
Despite remarkable advances in basic biomedical science that have led to improved patient care, there is a wide and persistent gap in the abilities of researchers and clinicians to understand and appreciate each other. In this Editorial, the authors, a scientist and a clinician, discuss the rift between practitioners of laboratory research and clinical medicine. Using their first-hand experience and numerous interviews throughout the United States, they explore the causes of this 'cultural divide'. Members of both professions use advanced problem-solving skills and typically embark on their career paths with a deeply felt sense of purpose. Nonetheless, differences in classroom education, professional training environments, reward mechanisms and sources of drive contribute to obstacles that inhibit communication, mutual respect and productive collaboration. More than a sociological curiosity, the cultural divide is a significant barrier to the bench-to-bedside goals of translational medicine. Understanding its roots is the first step towards bridging the gap.
尽管基础生物医学科学取得了显著进展，改善了患者的护理水平，但研究人员和临床医生在相互理解和欣赏方面仍存在很大且持久的差距。在这篇社论中，一位科学家和一位临床医生讨论了实验室研究人员和临床医学实践之间的裂痕。他们利用自己的第一手经验和在美国各地的多次采访，探讨了这种“文化鸿沟”的原因。这两个专业的成员都使用先进的解决问题的技能，并且通常带着强烈的使命感开始他们的职业生涯。尽管如此，课堂教育、专业培训环境、奖励机制和驱动力的来源差异导致了沟通、相互尊重和富有成效的合作的障碍。文化鸿沟不仅仅是一个社会学上的好奇，它也是转化医学从基础到临床目标的一个重大障碍。了解其根源是弥合这一差距的第一步。
