Beham A, Langsteger W, Schmid C, Lind P, Kronberger D
Institut für Pathologische Anatomie, Universität Graz.
Wien Klin Wochenschr. 1988 Apr 1;100(7):210-5.
Chronic invasive fibrous thyroiditis (Riedel's struma) is a very rare disease of unknown aetiology mainly affecting middle-aged or old female patients. An aggressive fibrosis partly or totally replaces normal thyroid gland tissue. The gland becomes stony hard, is not displaceable and, characteristically, the fibrous tissue penetrates the capsule and infiltrates into surrounding structures such as muscles, vessels, nerves and even the trachea. Riedel's struma is often associated with fibrotic processes in other parts of the body. The preoperative differential diagnosis includes malignant tumours and fibrosing stages of Hashimoto's disease, as well as subacute thyroiditis de Quervain. This paper reports the case of a 60-year-old woman suffering from Riedel's struma and discusses differential diagnostic aspects with regard to preoperative investigation and pathohistology.
慢性侵袭性纤维性甲状腺炎（里德尔甲状腺肿）是一种病因不明的极为罕见的疾病，主要影响中老年女性患者。一种侵袭性纤维化会部分或完全取代正常甲状腺组织。甲状腺变得如石头般坚硬，不可移动，其特征是纤维组织穿透包膜并浸润到周围结构，如肌肉、血管、神经甚至气管。里德尔甲状腺肿常与身体其他部位的纤维化过程相关。术前鉴别诊断包括恶性肿瘤、桥本氏病的纤维化阶段以及亚急性肉芽肿性甲状腺炎。本文报告了一名患有里德尔甲状腺肿的60岁女性病例，并讨论了术前检查和病理组织学方面的鉴别诊断问题。
