Harigopal Malini, Sahoo Sunati, Recant Wendy M, DeMay Richard M
Department of Pathology, New York-Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York, USA.
Diagn Cytopathol. 2004 Mar;30(3):193-7. doi: 10.1002/dc.10420.
The cytomorphological features of a case of Riedel's thyroiditis (Riedel's disease) in a 37-yr-old woman are reviewed. The patient presented with a diffusely enlarged thyroid gland with extension to carotid and jugular vessels bilaterally. A fine-needle aspiration of the right lobe of the thyroid demonstrated moderate cellularity with fragments of fibrous tissue with bland spindle-shaped cells and myofibroblasts. The patient subsequently underwent a bilateral subtotal thyroidectomy with removal of two-thirds of both lobes of the thyroid. A frozen section diagnosis of Riedel's disease was later confirmed on paraffin sections. Here we describe the cytological findings of a case of Riedel's disease and provide some helpful clues in distinguishing it from other forms of thyroiditis such as fibrosing variant of Hashimoto's thyroiditis, subacute thyroiditis, or granulomatous thyroiditis and from malignancy with which it can be confused both clinically and cytologically.
回顾了一名37岁女性里德尔甲状腺炎（里德尔病）病例的细胞形态学特征。患者表现为甲状腺弥漫性肿大，双侧延伸至颈动脉和颈静脉血管。对甲状腺右叶进行细针穿刺，结果显示细胞数量中等，伴有纤维组织碎片，其中有形态温和的梭形细胞和成肌纤维细胞。患者随后接受了双侧甲状腺次全切除术，切除了双侧甲状腺叶的三分之二。冰冻切片诊断为里德尔病，随后石蜡切片证实了该诊断。在此，我们描述了一例里德尔病的细胞学发现，并提供了一些有助于将其与其他形式的甲状腺炎（如桥本甲状腺炎的纤维化变体、亚急性甲状腺炎或肉芽肿性甲状腺炎）以及在临床和细胞学上可能与之混淆的恶性肿瘤相鉴别的有用线索。
