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一种针对儿科患者的新型对比敏感度测试:在眼部疾病和脑性视觉障碍中的可行性及检查者间可靠性

A New Contrast Sensitivity Test for Pediatric Patients: Feasibility and Inter-Examiner Reliability in Ocular Disorders and Cerebral Visual Impairment.

作者信息

Mayer D Luisa, Taylor Christopher Patrick, Kran Barry S

机构信息

New England College of Optometry, Boston, MA, USA.

Harvard Medical School, Boston, MA, USA.

出版信息

Transl Vis Sci Technol. 2020 Aug 20;9(9):30. doi: 10.1167/tvst.9.9.30. eCollection 2020 Aug.

DOI:10.1167/tvst.9.9.30
PMID:32879786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7442875/
Abstract

PURPOSE

Assess feasibility and interexaminer reliability of a new test of contrast sensitivity (CS) for pediatric populations.

METHODS

The Double Happy (DH) measures CS using a method similar to the Teller Acuity Cards. The schematic DH face is 16 degrees in diameter with features of 0.3 c/d and a channel frequency of 0.8 c/d. DH log CS is in 0.15 log unit steps, 0.05 to 2.1. Participants were 43 unselected patients, ages 2 to 18 years: 23 were diagnosed with ocular disorders only; 20 were diagnosed with cerebral visual impairment (CVI). Two examiners measured DH log CS. Visual acuity (VA) was also measured.

RESULTS

All 43 participants were tested for binocular DH logCS. Cohen's kappa values for interexaminer reliability were fair. The between examiner ICC was +0.92 ( < 0.001). The mean difference between examiners was near zero, and the 95% CI was -0.44 to 0.45 logCS. DH logCS was near normal in the ocular disorder group and reduced in the CVI group. VA was reduced in both groups. DH log CS and VA were correlated ( = -0.65). DH log CS was a marginally better predictor of diagnosis than VA.

CONCLUSIONS

DH logCS test was successful in a diverse pediatric population diagnosed with ocular disorders or CVI. Interexaminer reliability was comparable to that of adults tested previously using the same stimuli and methods. Both CS and VA are reduced in CVI.

TRANSLATIONAL RELEVANCE

CS and VA both should be tested in pediatric clinical populations, especially in those at risk of CVI.

摘要

目的

评估一种用于儿科人群的新的对比敏感度(CS)测试的可行性和检查者间可靠性。

方法

“双悦”(DH)使用一种类似于泰勒视力卡片的方法测量CS。示意性的DH脸直径为16度,特征为0.3 c/d,通道频率为0.8 c/d。DH对数CS以0.15对数单位步长变化,范围从0.05到2.1。参与者为43名未经挑选的2至18岁患者:23名仅被诊断患有眼部疾病;20名被诊断患有脑性视觉损害(CVI)。两名检查者测量DH对数CS。同时也测量了视力(VA)。

结果

对所有43名参与者进行了双眼DH对数CS测试。检查者间可靠性的科恩kappa值为中等。检查者间的组内相关系数(ICC)为+0.92(<0.001)。检查者之间的平均差异接近零,95%置信区间为-0.44至0.45对数CS。眼部疾病组的DH对数CS接近正常,而CVI组则降低。两组的VA均降低。DH对数CS与VA相关(=-0.65)。DH对数CS对诊断的预测略优于VA。

结论

DH对数CS测试在诊断患有眼部疾病或CVI的不同儿科人群中取得了成功。检查者间可靠性与先前使用相同刺激和方法测试的成年人相当。CVI患者的CS和VA均降低。

转化相关性

在儿科临床人群中,尤其是有CVI风险的人群中,应同时测试CS和VA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/626e889f9d84/tvst-9-9-30-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/370a0a9e775b/tvst-9-9-30-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/ceebc9d44516/tvst-9-9-30-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/a3849f7502e9/tvst-9-9-30-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/626e889f9d84/tvst-9-9-30-f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/370a0a9e775b/tvst-9-9-30-f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/ceebc9d44516/tvst-9-9-30-f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/a3849f7502e9/tvst-9-9-30-f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b30/7442875/626e889f9d84/tvst-9-9-30-f004.jpg

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