Syed Nafeez, Road Jeremy D, Ryerson Christopher J, Guenette Jordan A
Centre for Heart Lung InnovationProvidence Health Care Research Institute, The University of British Columbia, St. Paul's HospitalVancouverBCV6Z 1Y6Canada.
Department of Physical TherapyThe University of British ColumbiaVancouverBCV6T 1Z4Canada.
IEEE J Transl Eng Health Med. 2020 Aug 20;8:2700708. doi: 10.1109/JTEHM.2020.3018399. eCollection 2020.
To validate the Vibe actigraph in assessing sleep-wake patterns compared to polysomnography (PSG) in patients with COPD.
Nine stable COPD patients wore actigraphs while undergoing PSG. The correlation between total sleep time (TST), total sleep period (TSP), sleep onset latency (SOL), wake after sleep onset (WASO), and sleep efficiency was determined for corresponding measurements from the actigraph and PSG. Sensitivity, specificity, and positive and negative predictive values were calculated for the actigraph, considering PSG the gold standard. Levels of agreement between the variables of PSG and the actigraph were estimated using Bland-Altman plots.
A strong and statistically significant correlation was noted between PSG and the actigraph in detecting movement during sleep [mean activity score (counts)], TST and TSP (all r = 0.83; p = 0.005). The median agreement of sleep and wake counts between PSG and the actigraph was 73% and the Cohen's Kappa value was 0.66. The medians of sensitivity and specificity of the actigraph for detecting sleep versus PSG were 84 and 66%, respectively. The median positive and negative predictive values of the actigraph were 74 and 72%, respectively.
This study demonstrated that, under controlled laboratory conditions, the Vibe actigraph in its default settings is a promising tool for the detection of sleep-wake parameters in a small number of ambulatory patients with COPD. Clinical Impact: The actigraph used in this pilot study suggests that these devices could provide clinically relevant information in COPD to better understand the relationship between sleep and health in this population.
在慢性阻塞性肺疾病（COPD）患者中，与多导睡眠图（PSG）相比，验证Vibe活动记录仪在评估睡眠-觉醒模式方面的有效性。
9名病情稳定的COPD患者在进行PSG检查时佩戴活动记录仪。确定活动记录仪和PSG相应测量值之间总睡眠时间（TST）、总睡眠时长（TSP）、入睡潜伏期（SOL）、睡眠中觉醒时间（WASO）和睡眠效率的相关性。以PSG为金标准，计算活动记录仪的敏感性、特异性、阳性预测值和阴性预测值。使用Bland-Altman图估计PSG和活动记录仪变量之间的一致性水平。
在检测睡眠期间的活动[平均活动评分（计数）]、TST和TSP方面，PSG与活动记录仪之间存在强且具有统计学意义的相关性（所有r = 0.83；p = 0.005）。PSG和活动记录仪之间睡眠和觉醒计数的中位数一致性为73%，Cohen's Kappa值为0.66。活动记录仪检测睡眠与PSG相比的敏感性和特异性中位数分别为84%和66%。活动记录仪的阳性和阴性预测值中位数分别为74%和72%。
本研究表明，在受控的实验室条件下，默认设置的Vibe活动记录仪是检测少数非卧床COPD患者睡眠-觉醒参数的有前景的工具。临床影响：本初步研究中使用的活动记录仪表明，这些设备可为COPD患者提供临床相关信息，以更好地了解该人群睡眠与健康之间的关系。
