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加拿大肝硬化死亡率和发病率的降低:人口统计学差异及可能原因。

Reductions in liver cirrhosis mortality and morbidity in Canada: demographic differences and possible explanations.

作者信息

Mann R E, Smart R G, Anglin L

机构信息

Prevention Studies Department, Addiction Research Foundation, Toronto, Ontario, Canada.

出版信息

Alcohol Clin Exp Res. 1988 Apr;12(2):290-7. doi: 10.1111/j.1530-0277.1988.tb00197.x.

Abstract

In Canada, deaths from liver cirrhosis have declined by about 25% since 1974. To gain further insight into the nature of this decline, mortality rates for the years 1974-1984 and morbidity (hospital separation) rates for the years 1974-1980 were examined by age and sex and by province and sex. As well, survey data on drinking practices in Ontario were analyzed. Both mortality and morbidity declined over the time period involved, although variations over provinces, age groups, and sex were observed. The pattern of variations (largest declines in provinces with highest per capita alcohol consumption and in young to middle-aged males) strongly suggests decreased incidence of alcoholic liver cirrhosis. Among the factors which may be contributing to these declines are: the stabilization and small decreases in per capita consumption of alcohol; consumption pattern changes consistent with observed mortality and morbidity changes; expanded health promotion activities; and increases in the numbers of alcoholics receiving treatment.

摘要

自1974年以来,加拿大肝硬化导致的死亡率下降了约25%。为了进一步深入了解这种下降的本质,按年龄和性别以及按省份和性别,对1974年至1984年的死亡率和1974年至1980年的发病率(出院率)进行了研究。此外,还分析了安大略省饮酒习惯的调查数据。在所涉及的时间段内,死亡率和发病率均有所下降,不过在省份、年龄组和性别方面存在差异。变化模式(人均酒精消费量最高的省份以及年轻至中年男性的下降幅度最大)强烈表明酒精性肝硬化的发病率有所下降。可能导致这些下降的因素包括:人均酒精消费量趋于稳定并略有下降;消费模式的变化与观察到的死亡率和发病率变化一致;健康促进活动的扩大;以及接受治疗的酗酒者人数增加。

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