Senin U, Parnetti L, Mercuri M, Lupattelli G, Susta A, Ciuffetti G
Gerontology and Geriatric Department, Faculty of Medicine, University of Perugia, Italy.
Angiology. 1988 May;39(5):429-36. doi: 10.1177/000331978803900505.
A two-year follow-up on 118 atherosclerotic lesions of the extracranial carotid tract observed in 70 patients was carried out using real-time high-resolution echotomography. The following plaque characteristics were monitored: the echogenic patterns (soft, intermediate, hard, and mixed), the surface aspects, and the degree of stenosis. The aim of the study was to evaluate plaque evolution, in relation both to the degree of vessel stenosis produced and to the echostructural characteristics of the lesion. After two years 68% of the lesions remained unchanged while the degree of vessel stenosis increased in 32%; no case of regression was observed. Intrinsic factors appearing to condition an increase in degree of stenosis were "mixed" and "hard" echogenic pattern, an irregular lesion surface, and an initial degree of stenosis of more than 50%. A modification in the echogenic pattern, which generally tended to progress toward more highly reflecting echogenic levels was observed in 27% of the lesions studied.
对70例患者观察到的118处颅外颈动脉粥样硬化病变进行了为期两年的实时高分辨率超声断层扫描随访。监测了以下斑块特征：回声模式（软斑、中等回声斑、硬斑和混合斑）、表面情况和狭窄程度。本研究的目的是评估斑块演变情况，以及其与所导致的血管狭窄程度和病变回声结构特征的关系。两年后，68%的病变保持不变，而32%的病变血管狭窄程度增加；未观察到病变缩小的病例。似乎会导致狭窄程度增加的内在因素包括“混合”和“硬”回声模式、病变表面不规则以及初始狭窄程度超过50%。在所研究的病变中，27%观察到回声模式发生改变，总体上倾向于向更高回声水平发展。
