D'Alotto C, Pelz D M, Rankin R N
J Can Assoc Radiol. 1985 Sep;36(3):200-8.
Duplex ultrasonography and intravenous digital subtraction angiography (IV-DSA) were used as the initial diagnostic studies in 124 patients referred for evaluation of neurological disorders possibly related to carotid bifurcation disease in the neck. Conventional angiograms were subsequently performed in 29 patients. Diagnostic images were obtained in 100% of the angiograms, 94% of the duplex ultrasonograms and 89% of the IV-DSA studies. Using the angiogram as the reference standard for plaque detection, duplex ultrasonography had a sensitivity of 0.93 and specificity of 0.83. Doppler velocity ratio alone was used to detect all patients with angiographically demonstrated disease but demonstrated a specificity of only 0.35. IV-DSA showed a sensitivity of 0.93 and specificity of 0.91. IV-DSA and duplex ultrasonography agreed in the assessment of degree stenosis in over 90% of cases and we conclude that these two modalities have approximately the same sensitivity and specificity for detecting atherosclerotic disease at the carotid bifurcations.
124例因颈部可能与颈动脉分叉疾病相关的神经系统疾病前来评估的患者，最初采用双功超声检查和静脉数字减影血管造影（IV-DSA）进行诊断性研究。随后对29例患者进行了传统血管造影。血管造影的诊断图像获取率为100%，双功超声检查为94%，IV-DSA研究为89%。以血管造影作为检测斑块的参考标准，双功超声检查的敏感性为0.93，特异性为0.83。仅使用多普勒速度比检测血管造影证实疾病的所有患者，但特异性仅为0.35。IV-DSA的敏感性为0.93，特异性为0.91。在超过90%的病例中，IV-DSA和双功超声检查在评估狭窄程度方面意见一致，我们得出结论，这两种方法在检测颈动脉分叉处动脉粥样硬化疾病方面具有大致相同的敏感性和特异性。
