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[程序性血液透析及人尸体肾移植过程中的微循环形态学]

[Morphology of the lesser circulation during programmed hemodialysis and the transplantation of a human cadaveric kidney].

作者信息

Alekseevskikh Iu G, Kolybin V S

出版信息

Arkh Patol. 1988;50(3):60-6.

PMID:3288184
Abstract

The results of program-controlled hemodialysis (PCH) and cadaver kidney transplantation (CKT) were evaluated morphologically using 36 sections obtained from patients with end-stage chronic renal failure. For PCH-treated patients the findings indicated development of mixed secondary hypertension of the lungs associated with atherosclerotic involvement of the pulmonary artery and its branches, arteriolar rearrangements and visceral angiosclerosis. Morphologically, a successful CKT outcome resulted in late postoperative (in the time interval of 5 months--4.5 years) reduction of the signs typical for pulmonary vasculature affection with hypertension of the lesser circulation. This can suggest possibility of a reversible course of pulmonary hypertension in relevant patients.

摘要

利用从终末期慢性肾衰竭患者获取的36个切片,从形态学角度评估了程控血液透析(PCH)和尸体肾移植(CKT)的结果。对于接受PCH治疗的患者,研究结果表明出现了肺部混合性继发性高血压,伴有肺动脉及其分支的动脉粥样硬化累及、小动脉重塑和内脏血管硬化。从形态学上看,CKT成功的结果是术后晚期(在5个月至4.5年的时间间隔内)减轻了肺循环高血压所致肺血管病变的典型体征。这提示相关患者的肺动脉高压可能存在可逆病程。

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