Avner E D, Harmon W E, Grupe W E, Ingelfinger J R, Eraklis A J, Levey R H
Pediatrics. 1981 Mar;67(3):412-6.
The long-term mortality of chronic hemodialysis and renal transplantation was analyzed in all children treated for end-stage renal disease at Children's Hospital Medical Center over the pase 8 1/2 years. A total of 216 transplantation or dialysis courses in 120 patients were studied. No patients were excluded from treatment or analysis. Overall actuarial survival was 92% at six months, 90% at 12 months, and 89% at five years. When actuarial survival for each form of treatment was examined, patient survival was 100% at six months and 95% at five years for chronic hemodialysis; 92% at six months and five years for living related transplantation; and 88% at six months and 85% at five years for cadaveric transplantation. We conclude that most children with end-stage renal disease can be kept alive with current treatment programs, and that the mortality of chronic hemodialysis in children is comparable to that of renal transplantation.
在过去8年半的时间里，对儿童医院医疗中心所有接受终末期肾病治疗的儿童的慢性血液透析和肾移植的长期死亡率进行了分析。共研究了120例患者的216个移植或透析疗程。没有患者被排除在治疗或分析之外。总体精算生存率在6个月时为92%，12个月时为90%，5年时为89%。当检查每种治疗方式的精算生存率时，慢性血液透析患者在6个月时的生存率为100%，5年时为95%；活体亲属移植在6个月和5年时均为92%；尸体移植在6个月时为88%，5年时为85%。我们得出结论，大多数终末期肾病儿童通过目前的治疗方案可以存活，并且儿童慢性血液透析的死亡率与肾移植相当。
