Department of Radiology, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.
Division of Abdominal Radiology, Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
PLoS One. 2020 Sep 3;15(9):e0231431. doi: 10.1371/journal.pone.0231431. eCollection 2020.
To compare the radiation dose and the objective and subjective image quality of 80 kVp and 80/150 kVp with tin filter (80/Sn150 kVp) computed tomography (CT) in oncology patients.
One-hundred-and-forty-five consecutive oncology patients who underwent third-generation dual-source dual-energy CT of the abdomen for evaluation of malignant visceral, peritoneal, extraperitoneal, and bone tumor were retrospectively recruited. Two radiologists independently reviewed each observation in 80 kVp CT and 80/Sn150 kVp CT. Modified line-density profile of the tumor and contrast-to-noise ratio (CNR) were measured. Diagnostic confidence, lesion conspicuity, and subjective image quality were calculated and compared between image sets. The effective dose and size-specific dose estimate (SSDE) were calculated in the image sets.
Modified line-density profile analysis revealed higher attenuation differences between the tumor and normal tissue in 80 kVp CT than in 80/Sn150 kVp CT (127 vs. 107, P = 0.05). The 80 kVp CT showed increased CNR in the liver (8.0 vs. 7.6) and the aorta (18.9 vs. 16.3) than the 80/Sn150 kVp CT. The 80 kVp CT yielded higher enhancement of organs (4.9 ± 0.2 vs. 4.7 ± 0.4, P<0.001) and lesion conspicuity (4.9 ± 0.3 vs. 4.8 ± 0.5, P = 0.035) than the 80/Sn150 kVp CT; overall image quality and confidence index were comparable. The effective dose was reduced by 45.2% with 80 kVp CT (2.3 mSv ± 0.9) compared to 80/Sn150 kVp CT (4.1 mSv ± 1.5). The SSDE was 7.4 ± 3.8 mGy on 80/Sn150 kVp CT and 4.1 ± 2.2 mGy on 80 kVp CT.
The 80 kVp CT reduced the radiation dose by 45.2% in oncology patients while showing comparable or superior image quality to that of 80/Sn150 kVp CT for abdominal tumor evaluation.
比较 80kVp 和 80/Sn150kVp 带锡滤器(80/Sn150kVp)计算机断层扫描(CT)在肿瘤患者中的辐射剂量和客观及主观图像质量。
回顾性招募了 145 例连续行腹部第三代双源双能 CT 检查以评估恶性内脏、腹膜、腹膜后和骨肿瘤的肿瘤患者。两位放射科医生分别对 80kVp CT 和 80/Sn150kVp CT 中的每个观察结果进行了独立评估。测量肿瘤的改良线密度轮廓和对比噪声比(CNR)。计算并比较了两组图像的诊断信心、病变显示度和主观图像质量。计算了两组图像的有效剂量和体型特异性剂量估计值(SSDE)。
改良线密度轮廓分析显示,80kVp CT 中肿瘤与正常组织之间的衰减差异高于 80/Sn150kVp CT(127 比 107,P=0.05)。80kVp CT 显示肝脏(8.0 比 7.6)和主动脉(18.9 比 16.3)的 CNR 增加。80kVp CT 比 80/Sn150kVp CT 显示出更高的器官增强(4.9±0.2 比 4.7±0.4,P<0.001)和病变显示度(4.9±0.3 比 4.8±0.5,P=0.035)。总体图像质量和信心指数相当。与 80/Sn150kVp CT(4.1 mSv±1.5)相比,80kVp CT 的有效剂量降低了 45.2%(2.3 mSv±0.9)。80/Sn150kVp CT 的 SSDE 为 7.4±3.8 mGy,80kVp CT 的 SSDE 为 4.1±2.2 mGy。
80kVp CT 降低了肿瘤患者 45.2%的辐射剂量,同时在评估腹部肿瘤方面,图像质量与 80/Sn150kVp CT 相当或更好。