Diagnostic Imaging & Radiotherapy Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Department of Physics, Faculty of Science, Universiti Teknologi Malaysia, 81300, Johor Bharu, Johor, Malaysia.
Sci Rep. 2019 Mar 13;9(1):4374. doi: 10.1038/s41598-019-40758-5.
In this report we have evaluated radiation effective dose received by patients during ECG-gated CCTA examinations based on gender, heart rate, tube voltage protocol and body mass index (BMI). A total of 1,824 patients were retrospectively recruited (1,139 men and 685 women) and they were divided into Group 1 (CCTA with calcium scoring), Group 2 (CCTA without calcium scoring) and Group 3 (only calcium scoring), where the association between gender, heart rate, tube voltage protocol and body mass index (BMI) were analysed. Examinations were performed using a retrospective ECG-gated CCTA protocol and the effective doses were calculated from the dose length product with a conversion coefficient of 0.026 mSv.mGycm. No significant differences were observed in the mean effective dose between gender in all groups. The mean estimated dose was significantly higher when the heart rate was lower in Group 1 (p < 0.001) and Group 2 (p = 0.002). There were also significant differences between the mean effective dose in tube voltage protocol and BMI among the three groups. The mean effective dose was positively correlated with BMI (p < 0.001), but inversely related to the heart rate. This study supported the theory that a high heart rate, low tube voltage and low BMI could significantly reduce radiation dose exposure.
在本报告中,我们根据性别、心率、管电压协议和体重指数(BMI)评估了 ECG 门控 CCTA 检查中患者接受的辐射有效剂量。共回顾性招募了 1824 名患者(1139 名男性和 685 名女性),并将其分为三组:第 1 组(有钙化评分的 CCTA)、第 2 组(无钙化评分的 CCTA)和第 3 组(仅钙化评分),分析了性别、心率、管电压协议和体重指数(BMI)之间的关系。使用回顾性 ECG 门控 CCTA 协议进行检查,并从剂量长度乘积中使用转换系数 0.026 mSv.mGycm 计算有效剂量。在所有组中,性别之间的平均有效剂量无显著差异。在第 1 组(p < 0.001)和第 2 组(p = 0.002)中,心率较低时,估计的平均剂量显著较高。三组之间管电压协议和 BMI 之间的平均有效剂量也存在显著差异。平均有效剂量与 BMI 呈正相关(p < 0.001),但与心率呈负相关。本研究支持高心率、低管电压和低 BMI 可显著降低辐射剂量暴露的理论。