Galletta Diana, Califano Annamaria Immacolata, Micanti Fausta, Santangelo Gabriella, Santoriello Carmen, de Bartolomeis Andrea
Department of Head-Neck Care Unit of Psychiatry and Psychology "Federico II", University Hospital Naples, Italy.
Department of Head-Neck Care Unit of Psychiatry and Psychology "Federico II", University Hospital Naples, Italy.
J Psychiatr Res. 2020 Nov;130:372-380. doi: 10.1016/j.jpsychires.2020.06.016. Epub 2020 Jul 26.
Borderline intellectual functioning (BIF) is highly prevalent in patients with borderline personality disorder (BPD), but their relationship remains poorly understood. This retrospective study aimed to investigate the cognitive profile of BIF among people diagnosed with BPD. Clinical, demographic, and neuropsychological data of fifty-five outpatients with BPD were analyzed. The sample split into two groups: BPD with BIF (BIF+: n = 25; intelligence quotient - IQ - range: 71-84) and BPD without BIF (BIF-: n = 30; IQ range: 86-124). Between-group comparisons employed either parametric and non-parametric descriptive statistics, as necessary. Neuropsychological measures (Wechsler Adult Intelligence Scale-Revised - WAIS-R IQ, factor index, subtest scores) and cognitive performance deficits in the two groups were likewise compared aside, followed by Spearman's correlation test conducted on relevant metrics. The cognitive, but not the clinical and demographic profiles differed significantly between the two groups. BIF+ was associated with a specific pattern of verbal, attentive, and planning dysfunctions. The verbal comprehension index had the highest discriminative value for the presence of BIF in patients with BPD, and it was tightly associated with adaptive and social functioning. The neuropsychological assessment of BPD may be relevant to plan targeted interventions based on measures of cognitive functioning which could also serve to evaluate treatment efficacy and outcomes. Clinical implications and future directions are discussed.
边缘智力功能(BIF)在边缘型人格障碍(BPD)患者中极为普遍,但其二者之间的关系仍鲜为人知。这项回顾性研究旨在调查被诊断为BPD的人群中BIF的认知特征。分析了55名BPD门诊患者的临床、人口统计学和神经心理学数据。样本分为两组:伴有BIF的BPD(BIF+:n = 25;智商 - IQ - 范围:71 - 84)和不伴有BIF的BPD(BIF-:n = 30;智商范围:86 - 124)。必要时,组间比较采用参数和非参数描述性统计。同样比较了两组的神经心理学测量指标(韦氏成人智力量表修订版 - WAIS-R IQ、因子指数、分测验分数)和认知表现缺陷,随后对相关指标进行了Spearman相关性检验。两组之间在认知方面存在显著差异,但临床和人口统计学特征并无显著差异。BIF+与特定模式的语言、注意力和计划功能障碍有关。语言理解指数对BPD患者中BIF的存在具有最高的判别价值,并且它与适应和社会功能紧密相关。BPD的神经心理学评估可能与基于认知功能测量来规划针对性干预措施相关,这也有助于评估治疗效果和结果。文中讨论了临床意义和未来方向。