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在评估淋巴结细胞学标本中的大 B 细胞时的诊断注意事项。

Diagnostic Considerations in the Evaluation of Large B-Cells on Lymph Node Cytology Specimens.

机构信息

Department of Pathology, University of Michigan Hospital and Health System, Ann Arbor, Michigan, USA.

Department of Internal Medicine, University of Michigan Hospital and Health System, Ann Arbor, Michigan, USA.

出版信息

Acta Cytol. 2021;65(1):105-110. doi: 10.1159/000510322. Epub 2020 Sep 3.

Abstract

Fine needle aspiration (FNA) has become increasingly popular in the evaluation of lymph nodes for lymphoproliferative disorders, but there are limitations to accurate subclassification of lymphoma using morphology alone. This case aims to expand diagnostic considerations of large B-cell populations identified on FNA material. We also address the significance of Epstein-Barr virus (EBV) DNA in the workup of patients with suspected lymphoma by FNA.

摘要

细针抽吸(FNA)在评估淋巴增殖性疾病的淋巴结方面越来越受欢迎,但仅通过形态学对淋巴瘤进行准确的亚分类存在局限性。本病例旨在扩大对 FNA 材料中鉴定的大 B 细胞群体的诊断考虑。我们还讨论了 EBV DNA 在 FNA 检查疑似淋巴瘤患者中的意义。

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