Corbeil Serge
CSIRO, Australian Centre for Disease Preparedness, 5 Portarlington Rd, East Geelong, VIC 3219, Australia.
Pathogens. 2020 Sep 1;9(9):720. doi: 10.3390/pathogens9090720.
Abalone viral ganglioneuritis (AVG), caused by Haliotid herpesvirus-1 (HaHV-1; previously called abalone herpesvirus), is a disease that has been responsible for extensive mortalities in wild and farmed abalone and has caused significant economic losses in Asia and Australia since outbreaks occurred in the early 2000s. Researchers from Taiwan, China, and Australia have conducted numerous studies encompassing HaHV-1 genome sequencing, development of molecular diagnostic tests, and evaluation of the susceptibility of various abalone species to AVG as well as studies of gene expression in abalone upon virus infection. This review presents a timeline of the most significant research findings on AVG and HaHV-1 as well as potential future research avenues to further understand this disease in order to develop better management strategies.
鲍鱼病毒性神经节炎（AVG）由鲍疱疹病毒1型（HaHV-1；以前称为鲍鱼疱疹病毒）引起，是一种导致野生和养殖鲍鱼大量死亡的疾病，自21世纪初爆发以来，已在亚洲和澳大利亚造成重大经济损失。来自中国台湾和澳大利亚的研究人员进行了大量研究，包括HaHV-1基因组测序、分子诊断测试的开发、各种鲍鱼品种对AVG易感性的评估以及病毒感染后鲍鱼基因表达的研究。本综述介绍了关于AVG和HaHV-1最重要研究发现的时间线，以及未来潜在的研究途径，以进一步了解这种疾病，从而制定更好的管理策略。
