Sebastian Susan K, Singhal Aditya, Sharma Ankur, Doloi Pankajkumar
Department of ENT and Head & Neck Surgery, St Stephen's Hospital, Delhi, India.
J Otol. 2020 Sep;15(3):95-98. doi: 10.1016/j.joto.2019.12.001. Epub 2019 Dec 16.
Tuberculosis (TB) of the middle ear cleft (MEC) is a rare extra-pulmonary manifestation. Signs and symptoms of tuberculous otitis media are indistinguishable from that of non-tuberculous otitis media making early diagnosis difficult.
To study the clinical presentations, complications and effective diagnostic modalities in tuberculosis of middle ear cleft.
We retrospectively studied 10 patients diagnosed with chronic otitis media, unresponsive to 2 months conventional treatment. Pure tone audiogram, High resolution computed tomography (HRCT) of temporal bone, and AFB staining of ear discharge were done. All patients underwent mastoid surgery. AFB staining and histopathological examination of granulation tissue removed from the middle ear and mastoid were also done.
Clinical findings were mastoid swelling, facial palsy and post-aural fistula 3,4 & 2 patients respectively. All patients had persistent ear discharge and three had vertigo. Hearing loss was of moderate conductive type in five, sensorineural type in three and mixed type in two. HRCT of temporal bone revealed soft tissue density in MEC in 9 and evidence of bone destruction in 6 cases. Diagnosis of TB was confirmed either by (a) demonstration of AFB in ear discharge (4 patients)/tissue removed during surgery (4 patients) or (b) by demonstration of tuberculous granulomas with necrosis on histopathological examination of tissue from MEC (8 patients).
Tuberculosis should be suspected in all cases of chronic otitis media unresponsive to conventional treatment particularly in endemic areas. Histopathological examination and AFB staining of tissue removed during mastoid surgery are reliable diagnostic methods.
中耳裂结核(TB)是一种罕见的肺外表现。结核性中耳炎的体征和症状与非结核性中耳炎难以区分,导致早期诊断困难。
研究中耳裂结核的临床表现、并发症及有效的诊断方法。
我们回顾性研究了10例诊断为慢性中耳炎且对2个月常规治疗无反应的患者。进行了纯音听力图、颞骨高分辨率计算机断层扫描(HRCT)以及耳分泌物的抗酸杆菌(AFB)染色。所有患者均接受了乳突手术。还对从中耳和乳突切除的肉芽组织进行了AFB染色和组织病理学检查。
临床表现分别为乳突肿胀、面神经麻痹和耳后瘘管,各有3、4和2例患者出现。所有患者均有持续性耳漏,3例有眩晕。听力损失中,5例为中度传导性,3例为感音神经性,2例为混合性。颞骨HRCT显示9例中耳裂有软组织密度,6例有骨质破坏证据。结核的诊断通过以下方式得以证实:(a)耳分泌物(4例患者)/手术切除组织(4例患者)中发现AFB;或(b)中耳裂组织的组织病理学检查显示有结核性肉芽肿伴坏死(8例患者)。
在所有对常规治疗无反应的慢性中耳炎病例中,尤其是在流行地区,应怀疑结核。乳突手术中切除组织的组织病理学检查和AFB染色是可靠的诊断方法。