Ono Hiroshi, Mafune Ryo, Hayashi Taiyu, Misaki Yasushi, Kaneko Yukihiro, Saito Jumpei, Nagai Miki, Kato Hitoshi
Division of Cardiology, National Medical Center for Child Health and Development, Tokyo, Japan.
Division of Cardiovascular Surgery, National Medical Center for Child Health and Development, Tokyo, Japan.
J Cardiol Cases. 2020 Jun 2;22(3):107-109. doi: 10.1016/j.jccase.2020.05.008. eCollection 2020 Sep.
We used a paclitaxel-coated drug-eluting balloon (DEB) for pulmonary vein stenosis (PVS) after repair of total anomalous pulmonary venous return with asplenia. No adverse effect of paclitaxel was revealed and plasma concentration of paclitaxel was not elevated after intervention. Although progression of PVS slowed after dilatation with the DEB, stenosis recurred relentlessly, resulting in patient demise. This strategy may be safe for infantile cases, but requires further effective strategy, such as usage of larger sizes of DEBs. < Paclitaxel-coated drug-eluting balloons may be safely used for pulmonary vein stenosis after total anomalous pulmonary venous return repair in an infant with asplenia. However, their effectiveness is still limited.>.
我们对一名无脾综合征完全性肺静脉异位引流修复术后发生肺静脉狭窄（PVS）的患儿使用了紫杉醇涂层药物洗脱球囊（DEB）。未发现紫杉醇有不良反应，干预后紫杉醇血浆浓度未升高。尽管使用DEB扩张后PVS进展放缓，但狭窄仍持续复发，最终导致患者死亡。该策略对婴儿病例可能是安全的，但需要进一步有效的策略，如使用更大尺寸的DEB。<紫杉醇涂层药物洗脱球囊可安全用于无脾综合征婴儿完全性肺静脉异位引流修复术后的肺静脉狭窄。然而，其有效性仍然有限。>
